Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human s...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease worldwide, affecting over 30% of the global general population. Its progressive nature and association with other chronic diseases make...
BACKGROUND: Hyperlipidemia (HLP) exacerbates myocardial cell injury by impairing lipophagy, a crucial lipid metabolic process, thereby increasing the risk of acute myocardial infarction (AMI). This study aims to identify biomarkers associated with HL...
Childhood trauma constitutes a significant risk factor for adolescent anxiety, with emotion regulation playing a critical role. This large-scale longitudinal study (N = 2461 at baseline, with external validation) examined differential relationships b...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Aug 7, 2025
BET inhibitor is a novel strategy in tumor therapy based on targeting epigenetic mechanism. In recent decades, dozens of clinical trials have been conducted to validate the potential efficacy of the first-generation BET inhibitors in refractory cance...
BACKGROUND: ChatGPT and other large language models have emerged as new tools for patient education, yet their clinical safety and reliability remain unclear.
To enhance user interaction experience in furniture customization, this study optimizes an Internet of Things (IoT)-driven Artificial Intelligence (AI)-assisted design system. First, the study analyzes human-computer interaction theories in IoT envir...
BACKGROUND: Alzheimer's disease (AD) is the principal cause of dementia and requires the early diagnosis of people with mild cognitive impairment (MCI) who are at high risk of progressing. Early diagnosis is imperative for optimizing clinical managem...
BACKGROUND: Despite the National Health Insurance (NHI) system implemented in South Korea, concerns persist regarding access to health coverage for low-income households. To address this issue, this study aims to use machine learning-based data minin...
BMC medical informatics and decision making
Aug 7, 2025
BACKGROUND: Early diagnosis of Parkinson's disease (PD) can assist in designing efficient treatments. Reduced facial expressions are considered a hallmark of PD, making advanced artificial intelligence (AI) image processing a potential non-invasive c...
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