Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined. In this study, 53 immune-related key genes invol...
The Nancy histological index (NHI) is a measure of disease activity within colorectal biopsies and a predictor of clinical outcome in ulcerative colitis (UC). We measured interobserver agreement (IOA) during NHI scoring of 20 colorectal biopsies in U...
OBJECTIVE: This study examined the prevalence of pre-existing chronic conditions and their association with the receipt of specific cancer-directed treatments among older adults with incident primary Merkel Cell Carcinoma (MCC) using novel predictive...
The rise in online interactions has introduced multiple challenges, including confusion during virtual meetings and fatigue associated with prolonged video conferencing. To address these issues, this study advocates using computer graphics (CG) avata...
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is potentially curative for hematologic malignancies but is frequently complicated by relapse and immune-mediated complications, such as graft-versus-host disease (GVHD). Emerging ...
Clinical risk calculators consider sex as a binary variable. However, sex is a complex trait with anatomic, physiologic, and metabolic attributes that are not easily summarized in this manner [1]. We propose a continuous representation of sex, the EC...
Reproductive biology and endocrinology : RB&E
Jul 17, 2025
BACKGROUND: Conservative treatment remains a viable option for selected patients with ectopic pregnancy (EP), but failure may lead to rupture and serious complications. Currently, serum β-hCG is the main predictor for treatment outcomes, yet its accu...
BACKGROUND: Oral microbiota is a major etiological factor in the development of dental caries. Next-generation sequencing techniques have been widely used, generating vast amounts of data which is underexplored. The advancement of artificial intellig...
BACKGROUND: Unplanned postoperative intensive care unit admissions (UIAs) are rare events that cause significant challenges to perioperative workflow. We describe the development of a machine-learning derived model to predict UIAs using only widely u...
BACKGROUND: Parkinson's disease (PD) is a prevalent neurodegenerative condition, the effect of obesity on PD remains controversial. We aimed to investigate the associations of obesity patterns on PD and all-cause mortality, while developing machine l...
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