Clinical cancer research : an official journal of the American Association for Cancer Research
Jun 13, 2025
PURPOSE: Although the association between cytotoxic T lymphocytes and favorable prognosis in colorectal cancer is well established, the prognostic significance of B lymphocytes remains more ambiguous. This study aimed to assess the characteristics an...
BACKGROUND: Fibrosis is a common complication in Crohn's disease (CD), often leading to intestinal strictures. This study aims to explore the transcriptomic signature of fibrostenotic ileal CD for a comprehensive characterization of biological and ce...
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by increased stool frequency, rectal bleeding, and urgency. To streamline the quantitative assessment of histopathology using the Nancy Index in UC patients, we...
BACKGROUND: Breast cancer (BC) is the most prevalent cancer among women worldwide, and patients with metastasis to axillary lymph nodes (ALN) experience significantly lower survival rates. Current imaging-based screening methods often suffer from low...
BACKGROUND: Large language models (LLMs) are revolutionizing natural language processing, increasingly applied in clinical settings to enhance preoperative patient education.
BACKGROUND: Mosquito-borne diseases, such as malaria, dengue, and Zika, continue to pose significant threats to global health, resulting in millions of cases and thousands of deaths each year. Notably, only older mosquitoes can transmit these disease...
OBJECTIVES: Training public health personnel is crucial for enhancing the capacity of public health systems. However, existing research often falls short in providing a comprehensive theoretical framework and fails to account for the intricate interp...
Cardiovascular disease (CVD) is a primary cause of death in India, accounting for a significant portion of the global CVD burden. This study looks at statistics on heart disease mortality from the Institute for Health Metrics and Evaluation (IHME) fr...
BACKGROUND: Despite the high suicide rate in South Korea, older adults are reluctant to see a psychiatrist. Recently, text mining has gained popularity to detect depression in social media posts, but older adults rarely use social media. However, mor...
BACKGROUND: Mesenteric malperfusion (MMP) is an uncommon but devastating complication of acute aortic dissection (AAD) that combines 2 life-threatening conditions-aortic dissection and acute mesenteric ischemia. The complex pathophysiology of MMP pos...
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