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Development and temporal validation of a nomogram for predicting ICU 28-day mortality in middle-aged and elderly sepsis patients: An eICU database study.

PloS one
BACKGROUND AND OBJECTIVE: Despite advances in intensive care, sepsis remains a leading cause of mortality in intensive care unit (ICU) patients, especially middle-aged and elderly individuals. Given the limitations of conventional scoring systems and...

Development and performance of female breast cancer incidence risk prediction models: a systematic review and meta-analysis.

Annals of medicine
INTRODUCTION: Accurate breast cancer risk prediction is essential for early detection and personalized prevention strategies. While traditional models, such as Gail and Tyrer-Cuzick, are widely utilized, machine learning-based approaches may offer en...

Accurate deep-learning model to differentiate dementia severity and diagnosis using a portable electroencephalography device.

Scientific reports
Mild cognitive impairment (MCI) and dementia pose significant health challenges in aging societies, emphasizing the need for accessible, cost-effective, and noninvasive diagnostic tools. Electroencephalography (EEG) is a promising biomarker, but trad...

Exploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation.

Scientific reports
Cerebral amyloid angiopathy (CAA) and insomnia are age-related neurological disorders increasingly recognized as being closely associated. However, research on the shared genes and their biological mechanisms remains limited. This study aims to ident...

Innovating medical education using a cost effective and scalable VR platform with AI-Driven haptics.

Scientific reports
Virtual Reality (VR) technology offers a scalable and cost-effective approach to overcome the challenges of traditional medical training, including high expenses, limited resources, and ethical issues. This study presents a VR-based medical training ...

Application of machine learning algorithms and SHAP explanations to predict fertility preference among reproductive women in Somalia.

Scientific reports
Fertility preferences significantly influence population dynamics and reproductive health outcomes, particularly in low-resource settings, such as Somalia, where high fertility rates and limited healthcare infrastructure pose significant challenges. ...

Enhancing cardiac disease detection via a fusion of machine learning and medical imaging.

Scientific reports
Cardiovascular illnesses continue to be a predominant cause of mortality globally, underscoring the necessity for prompt and precise diagnosis to mitigate consequences and healthcare expenditures. This work presents a complete hybrid methodology that...

Prediction of birthweight with early and mid-pregnancy antenatal markers utilising machine learning and explainable artificial intelligence.

Scientific reports
Low birthweight (LBW) is a significant health challenge worldwide, as these neonates experience both short- and long-term disabilities. Factors affecting maternal and fetal health during early to mid-pregnancy can greatly influence fetal development....

Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort.

Scientific reports
The critical role of gut microbiota in human health and disease has been increasingly illustrated over the past decades, with a significant amount of research demonstrating an unmet need for self-monitor of the fecal microbial composition in an easil...