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Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome.
Proceedings of the National Academy of Sciences of the United States of America
Aug 11, 2025
People living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) experience heterogeneous and debilitating symptoms that lack sufficient biological explanation, compounded by the absence of accurate, noninvasive diagnostic tools. To add...
Building simplified cancer subtyping and prediction models with glycan gene signatures.
Cell reports methods
Aug 11, 2025
We identified a gene panel comprising 71 glycosyltransferases (GTs) that alter glycan patterns on cancer cells as they become more virulent. When these cancer-pattern GTs (CPGTs) were run through an algorithm trained on The Cancer Genome Atlas, they ...
Risk factors for tuberculosis treatment outcomes: a statistical learning-based exploration using the SINAN database with incomplete observations.
BMC medical informatics and decision making
Aug 11, 2025
BACKGROUND: Understanding early predictors of treatment outcomes allows better outcome prediction and resource allocation for efficient tuberculosis (TB) management.
An explainable predictive machine learning model for axillary lymph node metastasis in breast cancer based on multimodal data: A retrospective single-center study.
Journal of translational medicine
Aug 11, 2025
OBJECTIVE: To develop explainable machine learning models that integrate multimodal imaging and pathological biomarkers to predict axillary lymph node metastasis (ALNM) in breast cancer patients and assess their clinical utility.
Early detection of vascular catheter-associated infections employing supervised machine learning - a case study in Lleida region.
BMC medical informatics and decision making
Aug 11, 2025
Healthcare-associated infections (HAIs), particularly Vascular Catheter-Associated Infections (VCAIs), are a significant concern, accounting for over 7% of all infections and are often linked to medical devices. Early detection of VCAIs before invasi...
Leveraging BERT for embedding ICD codes from large scale cardiovascular EMR data to understand patient diagnostic patterns.
BMC medical informatics and decision making
Aug 11, 2025
The integration of electronic medical records (EMRs) with artificial intelligence (AI) is enhancing medical research, particularly in real-world evidence (RWE) studies. Extracting insights from coded medical data, such as ICD-10 codes, is essential f...
AI-assisted cervical cytology precancerous screening for high-risk population in resource-limited regions using a compact microscope.
Nature communications
Aug 11, 2025
Insufficient coverage of cervical cytology screening in resource-limited areas remains a major bottleneck for women's health, as traditional centralized methods require significant investment and many qualified pathologists. Using consumer-grade elec...
Unveiling the role of coagulation-related genes in acute myeloid leukemia prognosis and immune microenvironment through machine learning.
European journal of medical research
Aug 11, 2025
BACKGROUND: Acute Myeloid Leukemia (AML) is a highly heterogeneous hematologic malignancy influenced by various factors affecting prognosis. Recently, the role of coagulation-related genes in tumor biology has garnered increasing attention. This stud...
Multimodal radiomics in glioma: predicting recurrence in the peritumoural brain zone using integrated MRI.
BMC medical imaging
Aug 11, 2025
BACKGROUND: Gliomas exhibit a high recurrence rate, particularly in the peritumoural brain zone after surgery. This study aims to develop and validate a radiomics-based model using preoperative fluid-attenuated inversion recovery (FLAIR) and T1-weigh...
Artificial intelligence-assisted identification of condensing osteitis and idiopathic osteosclerosis on panoramic radiographs.
Scientific reports
Aug 11, 2025
Idiopathic osteosclerosis (IOS) and condensing osteitis (CO) represent radiopaque lesions often detected incidentally within the jaws, posing substantial diagnostic challenges due to their overlapping radiographic characteristics. The objective of th...
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