Metabolic dysfunction-associated fatty liver disease (MAFLD), a global epidemic affecting 25% of adults, is driven by immune-metabolic dysregulation, yet the causal mechanisms linking immune cell-specific gene perturbations to disease progression rem...
Mitotic cell cycle (MCC) is a critical process in cell growth and division, and dysregulation of MCC genes may contribute to tumorigenesis. In this study, to identify diagnostic and prognostic value of MCC genes, differentially expressed MCC genes be...
Tendon injury is a common and challenging clinical problem, and its healing process involves complex cellular and biological factors. Therefore, this study aims to reveal the mechanism of tendon healing and provide theoretical basis for clinical trea...
OBJECTIVE: This research aims to detect genes associated with the extracellular matrix (ECM) in idiopathic pulmonary fibrosis (IPF) using bioinformatics techniques and investigate their relationships with immune infiltration, with the goal of identif...
This study aimed to identify potential interacting genes between abdominal aortic aneurysm (AAA) and periodontitis. To achieve this, we obtained datasets of AAA and periodontitis from the GEO database, conducted differential analysis on the AAA datas...
Rheumatoid arthritis (RA) is increasingly prevalent among older adults, who often experience more severe symptoms and face significant treatment challenges. This study aims to identify specific genes associated with aging in RA and to analyze their i...
Acute respiratory distress syndrome (ARDS) is one of the most common and serious complications in the development of sepsis. Endoplasmic reticulum stress (ERS) plays an important role in the pathophysiologic process of sepsis-associated ARDS. The aim...
BACKGROUND: Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematox...
BACKGROUND: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an autoimmune disorder characterized by multi-organ involvement. Early identification and accurate diagnosis of AAV is crucial for improving prognosis. However, res...
The prompt diagnosis of pulmonary infections with unknown etiology in patients in severe condition remains a challenge due to the lack of rapid and effective diagnostic methods. While metatranscriptomic sequencing offers a powerful approach, its clin...
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