AIMC Topic: Glucocorticoids

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Augmented Intelligence Dermatology: Deep Neural Networks Empower Medical Professionals in Diagnosing Skin Cancer and Predicting Treatment Options for 134 Skin Disorders.

The Journal of investigative dermatology Mar 31, 2020
Although deep learning algorithms have demonstrated expert-level performance, previous efforts were mostly binary classifications of limited disorders. We trained an algorithm with 220,680 images of 174 disorders and validated it using Edinburgh (1,3...
Humans Anti-Bacterial Agents Photography Internship and Residency Drug Therapy, Computer-Assisted Skin Diseases Dermatology Image Interpretation, Computer-Assisted Datasets as Topic Deep Learning Young Adult Clinical Competence Adult Adolescent Male ROC Curve Middle Aged Glucocorticoids Antiviral Agents Female Antifungal Agents Skin Neoplasms Skin Dermoscopy Feasibility Studies Aged Dermatologists
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Patient discussions of glucocorticoid-related side effects within an online health community forum.

Annals of the rheumatic diseases Mar 25, 2020
Arthritis, Rheumatoid Social Media Data Mining Humans Machine Learning Glucocorticoids
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Support vector machines for explaining physiological stress response in Wood mice (Apodemus sylvaticus).

Scientific reports Feb 7, 2018
Physiological stress response is a crucial adaptive mechanism for prey species survival. This paper aims to identify the main environmental and/or individual factors better explaining the stress response in Wood mice, Apodemus sylvaticus. We analyzed...
Mice Support Vector Machine Body Weight Stress, Physiological Behavior, Animal Animals Glucocorticoids Feces Murinae
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The Role of Preoperative Steroids for Hearing Preservation Cochlear Implantation: Results of a Randomized Controlled Trial.

Audiology & neuro-otology Jan 13, 2018
OBJECTIVES: To determine whether preoperative steroids can improve hearing outcomes in cochlear implantation (CI).
Humans Female Aged Male Middle Aged Glucocorticoids Treatment Outcome Dexamethasone Prednisolone Hearing Preoperative Care Audiometry, Pure-Tone Cochlear Implantation Deafness
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Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.

Respiratory medicine Dec 13, 2017
BACKGROUND: Asthma is a heterogeneous and complex disease in both its clinical course and response to treatment. IL-13 is central to Type 2 inflammation and contributes to many features of asthma. In a previous Phase 2 study, lebrikizumab, an anti-IL...
Severity of Illness Index Injections, Subcutaneous Treatment Outcome Cyclopropanes Antibodies, Monoclonal Asthma Male Middle Aged Glucocorticoids Treatment Failure Quinolines Administration, Inhalation Anti-Asthmatic Agents Double-Blind Method Forced Expiratory Volume Acetates Sulfides Humans Female Adult
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Increased Cardiovascular Risk in Patients with Adrenal Insufficiency: A Short Review.

BioMed research international Dec 10, 2017
Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (AI) and increased cardiovascular risk (CVR). Patients with AI receive glucocorticoid (GC) replacement...
Adrenal Insufficiency Hydrocortisone Inflammation Mediators Prednisolone Cardiovascular System Risk Factors Cardiovascular Diseases Glucocorticoids Hormone Replacement Therapy Humans
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A randomised, phase III trial of once-daily fluticasone furoate/vilanterol 100/25 μg versus once-daily vilanterol 25 μg to evaluate the contribution on lung function of fluticasone furoate in the combination in patients with COPD.

Respiratory medicine Dec 2, 2016
BACKGROUND: The contribution of fluticasone furoate (FF) on lung function in the FF/vilanterol (VI) 100/25 μg combination has been demonstrated numerically, but not statistically.
Chlorobenzenes Administration, Inhalation Androstadienes Adrenergic beta-2 Receptor Agonists Benzyl Alcohols Pulmonary Disease, Chronic Obstructive Male Middle Aged Glucocorticoids Quality of Life Drug Combinations Double-Blind Method Forced Expiratory Volume Humans Drug Administration Schedule Female Kaplan-Meier Estimate Aged Adult
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Pharmacokinetics, Safety, and Tolerability of Once-Daily Intranasal Fluticasone Furoate and Levocabastine Administered Alone or Simultaneously as fluticasone Furoate/Levocabastine Fixed-Dose Combination.

Clinical pharmacology in drug development Dec 4, 2015
PURPOSE: The purpose of this study was to investigate potential systemic pharmacokinetic interactions between intranasal fluticasone furoate (FF) and levocabastine (LEVO) when delivered simultaneously via a metered atomizing spray pump.
Histamine H1 Antagonists, Non-Sedating Male Middle Aged Glucocorticoids Drug Combinations Biological Availability Cross-Over Studies Piperidines Androstadienes Administration, Intranasal Humans Female Young Adult Adult
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A tailored machine learning approach for mortality prediction in severe COVID-19 treated with glucocorticoids.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Sep 1, 2024
BACKGROUNDThe impact of severe COVID-19 pneumonia on healthcare systems highlighted the need for accurate predictions to improve patient outcomes. Despite the established efficacy of glucocorticoids (GCs), variable patient respons...
Humans Machine Learning Male Middle Aged Glucocorticoids Severity of Illness Index COVID-19 Drug Treatment COVID-19 Retrospective Studies Female SARS-CoV-2 Aged
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Efficacy of Pulse Methylprednisolone in Treatment of Acute Respiratory Distress Syndrome due to Malaria: A Randomized Controlled Clinical Trial.

The Journal of the Association of Physicians of India Nov 1, 2023
: To study the efficacy of pulse methylprednisolone (MPS) therapy in patients with malaria-associated acute respiratory distress syndrome (ARDS). : The study was a randomized, single-blind, placebo-controlled trial with a total sample size of 44 pati...
Treatment Outcome Respiratory Distress Syndrome Single-Blind Method Methylprednisolone Malaria Pulse Therapy, Drug Male Middle Aged Glucocorticoids Humans Respiration, Artificial Female Length of Stay Young Adult Adult
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