AIMC Topic: Healthy Volunteers

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Investigation of genotoxic effects of paraben in cultured human lymphocytes.

Drug and chemical toxicology Dec 27, 2017
Paraben is a phenolic derivative of benzoic acid extensively used as preservatives in food, pharmaceutical, and cosmetic industries due to its antimicrobial characteristics. The objective of this study was to evaluate the in vitro genotoxic effects o...
Micronucleus Tests Chromosome Aberrations Micronuclei, Chromosome-Defective Mitotic Index Sister Chromatid Exchange Lymphocytes Healthy Volunteers Parabens Comet Assay Mutagens Humans Cells, Cultured Dose-Response Relationship, Drug DNA Damage
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A Feasibility Study of SSVEP-Based Passive Training on an Ankle Rehabilitation Robot.

Journal of healthcare engineering Sep 17, 2017
OBJECTIVE: This study aims to establish a steady-state visual evoked potential- (SSVEP-) based passive training protocol on an ankle rehabilitation robot and validate its feasibility.
Feasibility Studies Motion Healthy Volunteers Brain-Computer Interfaces Humans Evoked Potentials, Visual Algorithms Female Male Reproducibility of Results Virtual Reality Young Adult Robotics Electroencephalography Signal Processing, Computer-Assisted Ankle Joint Ankle Photic Stimulation Fourier Analysis Rehabilitation
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MIT-Skywalker: considerations on the Design of a Body Weight Support System.

Journal of neuroengineering and rehabilitation Sep 6, 2017
BACKGROUND: To provide body weight support during walking and balance training, one can employ two distinct embodiments: support through a harness hanging from an overhead system or support through a saddle/seat type. This paper presents a comparison...
Humans Software Female Adult Biomechanical Phenomena Nervous System Diseases Walking Speed Orthotic Devices Bicycling Gait Disorders, Neurologic Male Robotics Walking Body Weight Healthy Volunteers
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How does wearable robotic exoskeleton affect overground walking performance measured with the 10-m and six-minute walk tests after a basic locomotor training in healthy individuals?

Gait & posture Aug 26, 2017
It is still unknown to what extent overground walking with a WRE is equivalent to natural overground walking without a WRE. Hence, the interpretability of the 10-m (10MWT) and six-minute (6MWT) walk tests during overground walking with a WRE against ...
Humans Female Adult Male Locomotion Spinal Cord Injuries Exoskeleton Device Physical Therapy Modalities Walk Test Time Factors Robotics Equipment Design Walking Healthy Volunteers
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Detection of lung cancer in exhaled breath with an electronic nose using support vector machine analysis.

Journal of breath research Aug 21, 2017
Lung cancer is one of the most common malignancies and has a low 5-year survival rate. There are no cheap, simple and widely available screening methods for the early diagnostics of lung cancer. The aim of this study was to determine whether analysis...
Neoplasm Staging Healthy Volunteers Breath Tests Exhalation Electronic Nose Humans Female Aged Adult Pulmonary Disease, Chronic Obstructive Male Middle Aged Case-Control Studies Lung Neoplasms Support Vector Machine
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A Control Scheme to Minimize Muscle Energy for Power Assistant Robotic Systems Under Unknown External Perturbation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society Jul 5, 2017
This paper proposes a novel control method to minimize muscle energy for power-assistant robotic systems that support the intended motions of a user under unknown external perturbations, using surface electromyogram (sEMG) signals. Conventional contr...
Biomechanical Phenomena Male Muscle, Skeletal Robotics Elbow Joint Humans Algorithms Adult Wrist Joint Signal Processing, Computer-Assisted Electromyography Torque Activities of Daily Living Healthy Volunteers
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KAPS (kinematic assessment of passive stretch): a tool to assess elbow flexor and extensor spasticity after stroke using a robotic exoskeleton.

Journal of neuroengineering and rehabilitation Jun 19, 2017
BACKGROUND: Spasticity is a common sequela of stroke. Traditional assessment methods include relatively coarse scales that may not capture all characteristics of elevated muscle tone. Thus, the aim of this study was to develop a tool to quantitativel...
Humans Female Aged Aged, 80 and over Young Adult Adult Sensitivity and Specificity Stroke Rehabilitation Physical Examination Muscle Spasticity Elbow Stroke Healthy Volunteers Range of Motion, Articular Exoskeleton Device Biomechanical Phenomena Male Middle Aged Adolescent Robotics
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Modifying upper-limb inter-joint coordination in healthy subjects by training with a robotic exoskeleton.

Journal of neuroengineering and rehabilitation Jun 12, 2017
BACKGROUND: The possibility to modify the usually pathological patterns of coordination of the upper-limb in stroke survivors remains a central issue and an open question for neurorehabilitation. Despite robot-led physical training could potentially ...
Physical Education and Training Stroke Rehabilitation Gravitation Psychomotor Performance Joints Humans Movement Algorithms Exoskeleton Device Upper Extremity Female Young Adult Adult Biomechanical Phenomena Male Posture Robotics Prosthesis Design Healthy Volunteers
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Extracting aerobic system dynamics during unsupervised activities of daily living using wearable sensor machine learning models.

Journal of applied physiology (Bethesda, Md. : 1985) Jun 8, 2017
Physical activity levels are related through algorithms to the energetic demand, with no information regarding the integrity of the multiple physiological systems involved in the energetic supply. Longitudinal analysis of the oxygen uptake (V̇o) by w...
Activities of Daily Living Healthy Volunteers Humans Machine Learning Young Adult Adult Male Wearable Electronic Devices Oxygen Consumption
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Toward Multimodal Human-Robot Interaction to Enhance Active Participation of Users in Gait Rehabilitation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society May 11, 2017
Robotic exoskeletons for physical rehabilitation have been utilized for retraining patients suffering from paraplegia and enhancing motor recovery in recent years. However, users are not voluntarily involved in most systems. This paper aims to develo...
Humans Algorithms Adult Biomechanical Phenomena Male Gait Disorders, Neurologic Central Pattern Generators Evoked Potentials, Somatosensory Robotics Electromyography Gait Healthy Volunteers Brain-Computer Interfaces Locomotion Leg Exoskeleton Device Patient Participation Stroke Rehabilitation
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