AIMC Topic: Humans

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A numerical treatment through Bayesian regularization neural network for the chickenpox disease model.

Computers in biology and medicine
OBJECTIVES: The current research investigations designates the numerical solutions of the chickenpox disease model by applying a proficient optimization framework based on the artificial neural network. The mathematical form of the chickenpox disease...

Discovering Vitamin-D-Deficiency-Associated Factors in Korean Adults Using KNHANES Data Based on an Integrated Analysis of Machine Learning and Statistical Techniques.

Nutrients
: Vitamin D deficiency (VDD) is a global health concern associated with metabolic disease and immune dysfunction. Despite known risk factors like limited sun exposure, diet, and lifestyle, few studies have explored these factors comprehensively on a ...

A Novel Deep Learning-Based (3D U-Net Model) Automated Pulmonary Nodule Detection Tool for CT Imaging.

Current oncology (Toronto, Ont.)
BACKGROUND: Precise detection and characterization of pulmonary nodules on computed tomography (CT) is crucial for early diagnosis and management.

Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study.

Arthritis research & therapy
OBJECTIVE: The aim of this study was to investigate the correlation between age, red cell distribution width (RDW) levels, and 180-day and 1-year mortality in giant cell arteritis (GCA) patients hospitalized or admitted to the ICU.

AI versus human-generated multiple-choice questions for medical education: a cohort study in a high-stakes examination.

BMC medical education
BACKGROUND: The creation of high-quality multiple-choice questions (MCQs) is essential for medical education assessments but is resource-intensive and time-consuming when done by human experts. Large language models (LLMs) like ChatGPT-4o offer a pro...

Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients.

BMC pulmonary medicine
BACKGROUND: Identification of distinct clinical phenotypes of diseases can guide personalized treatment. This study aimed to classify hospitalized COVID-19 pneumonia subgroups using an unsupervised machine learning approach.

Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients.

Scientific reports
Post-Liver transplantation (LT) survival rates stagnate, with biliary complications (BC) as a major cause of death. We analyzed longitudinal data with a median 19-month follow-up. BC was diagnosed with ultrasounds and MRCP. Missing data was imputed u...

Adaptive genetic algorithm based deep feature selector for cancer detection in lung histopathological images.

Scientific reports
Cancer is a global health concern because of a significant mortality rate and a wide range of affected organs. Early detection and accurate classification of cancer types are crucial for effective treatment. Imaging tests on different image modalitie...

An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets.

Scientific data
Although rare diseases (RDs) affect over 260 million individuals worldwide, low data quality and scarcity challenge effective care and research. This work aims to harmonise the Common Data Set by European Rare Disease Registry Infrastructure, Health ...

Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression.

Nature communications
Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. Here, we develop MnM, an efficient machine learning-based tool that allows disentangling scRT profiles from heterogenous samples. We use single-cell c...