AIMC Topic: Humans
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Whole‑exome evolutionary profiling of osteosarcoma uncovers metastasis‑related driver mutations and generates an independently validated predictive classifier.
Journal of translational medicine
Jul 7, 2025
BACKGROUND: Osteosarcoma is the most common primary malignant bone tumor, with high invasiveness and metastatic potential and a poor prognosis in patients with metastatic cancer. Despite the rapid advancements in genomics in recent years that provide...
Medical simulation: an essential tool for training, diagnosis, and treatment in the 21st century.
BMC medical education
Jul 7, 2025
BACKGROUND: Medical simulation is a global trend that improves disease interpretation, diagnostic skills, and clinical abilities, transforming them into skills for the practitioner. Simulator classes should be part of continuing medical education, ge...
Multilayer perceptron deep learning radiomics model based on Gd-BOPTA MRI to identify vessels encapsulating tumor clusters in hepatocellular carcinoma: a multi-center study.
Cancer imaging : the official publication of the International Cancer Imaging Society
Jul 7, 2025
OBJECTIVES: The purpose of this study is to mainly develop a predictive model based on clinicoradiological and radiomics features from preoperative gadobenate-enhanced (Gd-BOPTA) magnetic resonance imaging (MRI) using multilayer perceptron (MLP) deep...
Association of dietary quality, biological aging, progression and mortality of cardiovascular-kidney-metabolic syndrome: insights from mediation and machine learning approaches.
Nutrition journal
Jul 7, 2025
BACKGROUND: To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome.
Gender difference in cross-sectional area and fat infiltration of thigh muscles in the elderly population on MRI: an AI-based analysis.
European radiology experimental
Jul 7, 2025
BACKGROUND: Aging alters musculoskeletal structure and function, affecting muscle mass, composition, and strength, increasing the risk of falls and loss of independence in older adults. This study assessed cross-sectional area (CSA) and fat infiltrat...
Dynamicasome-a molecular dynamics-guided and AI-driven pathogenicity prediction catalogue for all genetic mutations.
Communications biology
Jul 7, 2025
Advances in genomic medicine accelerate the identification of mutations in disease-associated genes, but the pathogenicity of many mutations remains unknown, hindering their use in diagnostics and clinical decision-making. Predictive AI models are ge...
Autonomous screening of infants at high risk for neurodevelopmental impairments using a radar sensor and machine learning.
Scientific reports
Jul 7, 2025
Neurodevelopmental impairments (NDIs) are significant long-term complications in preterm infants. While early recognition of infants at high risk for NDIs is essential for enabling timely intervention, it remains a challenging endeavor. Autonomous sc...
Machine learning identifies KRT8 dysregulation and endothelial remodeling in Moyamoya disease.
Scientific reports
Jul 7, 2025
Moyamoya disease (MMD) is a rare occlusive cerebrovascular disease, and its pathological mechanism remains unclear at present. The abnormal vascular remodeling may be involved in vascular endothelial cells. In this study, RNA seq was performed on the...
Deep learning-based video analysis for automatically detecting penetration and aspiration in videofluoroscopic swallowing study.
Scientific reports
Jul 7, 2025
The videofluoroscopic swallowing study (VFSS) is the gold standard for diagnosing dysphagia, but its interpretation is time-consuming and requires expertise. This study developed a deep learning model for automatically detecting penetration and aspir...
Advanced bioactuator selection for efficient human motion simulation in biohybrid robots using CSF dynamic knowledge.
Scientific reports
Jul 7, 2025
The selection of the most efficient actuator for biohybrid robots necessitates the implementation of precise and reliable decision-making (DM) methods. Dynamic aggregation operators (AOs) provide flexibility and consistency in DM by embracing time-de...
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