Journal of chemical information and modeling
Aug 28, 2025
Antibody-antigen interaction prediction is essential for therapeutic development but remains experimentally costly. The dynamic conformational changes essential to antibody-antigen binding are often missed by structure-based methods relying on static...
Proceedings of the National Academy of Sciences of the United States of America
Aug 28, 2025
Human learning embodies a striking duality: Sometimes, we can rapidly infer and compose logical rules, benefiting from structured curricula (e.g., in formal education), while other times, we rely on an incremental approach or trial-and-error, learnin...
Proceedings of the National Academy of Sciences of the United States of America
Aug 28, 2025
With rapid advances in large language models (LLMs), there has been an increasing application of LLMs in creative content ideation and generation. A critical question emerges: can current LLMs provide ideas that are diverse enough to truly bolster co...
BACKGROUND: Systemic lupus erythematosus (SLE) is a life-threatening, multisystem autoimmune disease. Biologic therapy is a promising treatment for SLE. However, public understanding of this therapy is still insufficient, and the quality of related i...
BACKGROUND: To evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images derived from cone-beam CT (CBC...
BACKGROUND: Intra-aortic balloon pump (IABP) implantation in the perioperative period of cardiac surgery is an auxiliary treatment for cardiogenic shock. However, there is a lack of effective prediction models for preoperative IABP implantation.
Heydari et al. present an intriguing study examining the role of three long non-coding RNAs (lncRNAs)-H19, taurine upregulated gene 1 (TUG1), and colorectal neoplasia differentially expressed (CRNDE)-in the context of Coronavirus Disease 2019 (COVID-...
BACKGROUND: Suicide represents a significant challenge to public health that calls for a suitable intervention from the healthcare sector. Despite the typically low suicide rate among most Muslim nations, research indicates that there is an increase ...
BACKGROUND: The Anemia Control Model (ACM) is a decision support system powered by an artificial intelligence core designed to assist nephrologists in managing anemia therapy for in-center hemodialysis (HD) patients. This study aims to evaluate the c...
Extracting time-varying latent variables from computational cognitive models plays a key role in uncovering the dynamic cognitive processes that drive behaviors. However, existing methods are limited to inferring latent variable sequences in a relati...
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