AIMC Topic: Humans

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Benchmarking the Confidence of Large Language Models in Answering Clinical Questions: Cross-Sectional Evaluation Study.

JMIR medical informatics
BACKGROUND: The capabilities of large language models (LLMs) to self-assess their own confidence in answering questions within the biomedical realm remain underexplored.

Use of Virtual Reality in the Pediatric Perioperative Setting and for Induction of Anesthesia: Mixed Methods Pilot Feasibility Study.

JMIR perioperative medicine
BACKGROUND: Children commonly experience high levels of anxiety prior to surgery. This distress is associated with postoperative maladaptive behaviors. Virtual reality (VR) is an innovative tool for reducing anxiety and pain during various medical pr...

Celluloepidemiology-A paradigm for quantifying infectious disease dynamics on a population level.

Science advances
To complement serology as a tool in public health interventions, we introduced the "celluloepidemiology" paradigm where we leveraged pathogen-specific T cell responses at a population level to advance our epidemiological understanding of infectious d...

AI-assisted diffuse correlation tomography for identifying breast cancer.

Journal of biomedical optics
SIGNIFICANCE: Diffuse correlation tomography (DCT) is an emerging technique for the noninvasive measurement of breast microvascular blood flow, whereas its capability to categorize benign and malignant breast lesions has not been extensively validate...

AI-based volumetric six-tissue body composition quantification from CT cardiac attenuation scans for mortality prediction: a multicentre study.

The Lancet. Digital health
BACKGROUND: CT attenuation correction (CTAC) scans are routinely obtained during cardiac perfusion imaging, but currently only used for attenuation correction and visual calcium estimation. We aimed to develop a novel artificial intelligence (AI)-bas...

Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization.

Nature cardiovascular research
Large-cohort imaging and diagnostic studies often assess cardiac function but overlook underlying biological mechanisms. Cardiac digital twins (CDTs) are personalized physics-constrained and physiology-constrained in silico representations, uncoverin...

Emerging research themes in ferroptosis research for non-small cell lung cancer: a bibliometric and visualized analysis.

Frontiers in immunology
BACKGROUND: Ferroptosis, an iron-dependent form of regulated cell death, has garnered significant attention as a potential therapeutic target in oncology due to its unique mechanism involving lipid peroxidation and reactive oxygen species accumulatio...

Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding.

Frontiers in immunology
INTRODUCTION: Lyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the US and increasing incidence. Differentiating Lyme disease, especially in its early stages, f...

Robust performances of a nocturnal long-term ECG algorithm for the evaluation of sleep apnea syndrome: A pilot study.

PloS one
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is one of the most common sleep disorders affecting nearly one billion of the global adult population, making it a major public health issue. Even if in-lab polysomnography (PSG) remains the gold stan...

The neuronal chaperone proSAAS is highly expressed in the retina.

PloS one
The many layers of the neuroretina contain a complex, interconnected network of specialized neurons that both process visual stimuli and conduct processed information to higher brain areas. Neural networks rely on proteostatic control mechanisms to m...