AIMC Topic: Insulin Resistance

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High triglycerides to HDL-cholesterol ratio is associated with insulin resistance in normal-weight healthy adults.

Diabetes & metabolic syndrome
AIM: To evaluate the association between high triglyceride/HDL-cholesterol (TG/HDL-C) ratio and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in normal-weight healthy adults.

Triglycerides and glucose index as an insulin resistance marker in a sample of healthy adults.

Diabetes & metabolic syndrome
AIM: To assess the association between elevated triglycerides/glucose index (TGI) and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of healthy adults.

Association between vitamin D deficiency and insulin resistance markers in euthyroid non-diabetic individuals.

Diabetes & metabolic syndrome
AIM: To evaluate the association between vitamin D deficiency and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in euthyroid non-diabetic individuals.

Improved perfusion pattern score association with type 2 diabetes severity using machine learning pipeline: Pilot study.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Type 2 diabetes mellitus (T2DM) is associated with alterations in the blood-brain barrier, neuronal damage, and arterial stiffness, thus affecting cerebral metabolism and perfusion. There is a need to implement machine-learning methodolog...

Plasminogen activator inhibitor-1 is associated with the metabolism and development of advanced colonic polyps.

Translational research : the journal of laboratory and clinical medicine
Implications of plasminogen activator inhibitor-1 (PAI-1) in colonic polyps remain elusive. A prospective study was conducted with 188 consecutive subjects who underwent colonoscopy at a tertiary referral center. Biochemical parameters, serum PAI-1 l...

Fuzzy set-based generalized multifactor dimensionality reduction analysis of gene-gene interactions.

BMC medical genomics
BACKGROUND: Gene-gene interactions (GGIs) are a known cause of missing heritability. Multifactor dimensionality reduction (MDR) is one of most commonly used methods for GGI detection. The generalized multifactor dimensionality reduction (GMDR) method...

The effect of vitamin D supplementation on insulin resistance, visceral fat and adiponectin in vitamin D deficient women with polycystic ovary syndrome: a randomized placebo-controlled trial.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
INTRODUCTION: Low plasma 25-hydroxy-vitamin D (25OHD) is associated with polycystic ovary syndrome (PCOS). Vitamin D deficiency may contribute to the development of insulin resistance, visceral fat and low level of adiponectin which are common featur...

Effect of a short-term physical activity intervention on liver fat content in obese children.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Nonalcoholic fatty liver disease is the most common chronic liver disease and can present with advanced fibrosis or nonalcoholic steatohepatitis. The purpose of this study was to investigate the effect of a 7-day intense physical activity interventio...

Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans.

Metabolism: clinical and experimental
BACKGROUND: Loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result from circulating lipids (triacylglycerols [TG] or free fatty acids) and/or adipoc...