AIMC Topic: Insulin Resistance
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The effect of vitamin D supplementation on insulin resistance, visceral fat and adiponectin in vitamin D deficient women with polycystic ovary syndrome: a randomized placebo-controlled trial.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Dec 22, 2017
INTRODUCTION: Low plasma 25-hydroxy-vitamin D (25OHD) is associated with polycystic ovary syndrome (PCOS). Vitamin D deficiency may contribute to the development of insulin resistance, visceral fat and low level of adiponectin which are common featur...
A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.
Nutrients
Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Cytokines
Animals
Diet, High-Fat
Lipids
Coffea
Non-alcoholic Fatty Liver Disease
Alkaloids
Diterpenes
Caffeic Acids
Carbon-13 Magnetic Resonance Spectroscopy
Dietary Sucrose
Rats, Sprague-Dawley
Disease Models, Animal
Metabolic Syndrome
Dietary Supplements
Liver
Blood Glucose
Insulin
Time Factors
Insulin Resistance
Seeds
Effect of a short-term physical activity intervention on liver fat content in obese children.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Dec 20, 2017
Nonalcoholic fatty liver disease is the most common chronic liver disease and can present with advanced fibrosis or nonalcoholic steatohepatitis. The purpose of this study was to investigate the effect of a 7-day intense physical activity interventio...
Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans.
Metabolism: clinical and experimental
Dec 19, 2017
BACKGROUND: Loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result from circulating lipids (triacylglycerols [TG] or free fatty acids) and/or adipoc...
Resolution of type 2 diabetes after sleeve gastrectomy: a 2-step hypothesis.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Dec 14, 2017
BACKGROUND: Weight loss (WL) and altered gut hormonal levels are involved in glucose homeostasis after laparoscopic sleeve gastrectomy (LSG).
Putative identification of components in Zengye Decoction and their effects on glucose consumption and lipogenesis in insulin-induced insulin-resistant HepG2 cells.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 12, 2017
Zengye Decoction (ZYD) is a well-known traditional medicine in China used for treating diseases associated with "Yin deficiency" such as diabetes. However, little information is available on its components, pharmacological effects and underlying mech...
Relationship Between Serum Macrophage Migration Inhibitory Factor Level and Insulin Resistance, High-Sensitivity C-Reactive Protein and Visceral Fat Mass in Prediabetes.
The American journal of the medical sciences
Oct 26, 2017
BACKGROUND: Growing evidence suggest that macrophage migration inhibitory factor (MIF) plays a vital role in glucose metabolism. We aimed to ascertain whether MIF levels are altered in subjects with prediabetes and also to determine the relationship ...
Defining and characterizing the critical transition state prior to the type 2 diabetes disease.
PloS one
Jul 7, 2017
BACKGROUND: Type 2 diabetes mellitus (T2DM), with increased risk of serious long-term complications, currently represents 8.3% of the adult population. We hypothesized that a critical transition state prior to the new onset T2DM can be revealed throu...
NIRCa: An artificial neural network-based insulin resistance calculator.
Pediatric diabetes
Jun 19, 2017
BACKGROUND: Direct measurement of insulin sensitivity in children with type 1 diabetes is cumbersome and time consuming.
Cross-Sectional Studies
Male
Adolescent
Child
Insulin Resistance
Machine Learning
Female
Reproducibility of Results
Young Adult
Adult
Diabetic Angiopathies
Random Allocation
Multivariate Analysis
Glucose Clamp Technique
Prehypertension
Puberty
Computational Biology
Diabetes Mellitus, Type 1
Hypertension
Predictive Value of Tests
Humans
Neural Networks, Computer
The effect of genistein on glucose control and insulin sensitivity in postmenopausal women: A meta-analysis.
Maturitas
Dec 28, 2016
Preclinical studies have revealed the beneficial effects of genistein in pancreatic β-cell functions. The results of randomized controlled trials (RCTs) in assessing the effects of genistein on glucose metabolism are inconsistent, however. The aim of...
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