AIMC Topic: Interleukin-6

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[Optimization and evaluation of an inflammatory cell model in LPS-stimulated PMA-differentiated THP-1 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology Nov 1, 2017
Objective To develop an optimal inflammatory cell model from lipopolysaccharide (LPS)-stimulated phorbol ester (PMA)-differentiated THP-1 cells, and investigate its response to anti-inflammatory agent phosphodiesterase inhibitor rolipram. Methods THP...
Models, Biological Interleukin-6 THP-1 Cells Lipopolysaccharides Inflammation Mediators Cell Differentiation Tetradecanoylphorbol Acetate Anti-Inflammatory Agents Leukemia, Monocytic, Acute Humans Phosphodiesterase 4 Inhibitors Tumor Necrosis Factor-alpha Rolipram Macrophages
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[MiR-142-3p inhibits lipopolysaccharide-induced inflammatory response in human periodontal ligament cells through targeting IRAK1].

Shanghai kou qiang yi xue = Shanghai journal of stomatology Dec 1, 2016
PURPOSE: To investigate the effects of miR-142-3p overexpression on secretion of inflammatory factors in human periodontal ligament cells (hPDLCs) induced by lipopolysaccharide (LPS) and its underlying mechanism.
NF-kappa B Periodontal Ligament Transfection Interleukin-1 Receptor-Associated Kinases Lipopolysaccharides Cell Line Tumor Necrosis Factor-alpha MicroRNAs Interleukin-6 Inflammation Signal Transduction Humans
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Dilemma: Correlation Between Serum Level of Hepcidin and IL-6 in Anemic Myeloma Patients.

Medical archives (Sarajevo, Bosnia and Herzegovina) Dec 1, 2016
INTRODUCTION: Anemia occurs in 60% to 80 % of patients with newly diagnosed myeloma multiplex (MM). The cause of anemia in MM is probably multi factorial and involved among the others hepcidin and some cytokines, especially interleukine-6. Anemia in ...
Hemoglobins Anemia Multiple Myeloma Transferrin Predictive Value of Tests Sensitivity and Specificity Iron Male Ferritins Middle Aged Hepcidins Humans Interleukin-6 Anti-Infective Agents Prospective Studies Biomarkers Prognosis Female Aged Aged, 80 and over Adult
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The co-regulators SRC-1 and SMRT are involved in interleukin-6-induced androgen receptor activation.

European cytokine network Nov 1, 2016
BACKGROUND: The androgen receptor (AR) can be stimulated by interleukin-6 (IL-6) in the absence of androgens to induce prostate cancer progression. The purpose of this study was to investigate whether the co-activator steroid receptor coactivator-1 (...
Cell Line, Tumor Neoplasm Proteins Prostatic Neoplasms Receptors, Androgen Humans Interleukin-6 Male Nuclear Receptor Co-Repressor 2 Nuclear Receptor Coactivator 1
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Cerebrospinal fluid ferritin concentration in patients with purulent, bacterial meningitis – own observations.

Przeglad epidemiologiczny Jan 1, 2016
THE AIM: The aim of the study was to evaluate the usefulness of cerebrospinal fluid (CSF) ferritin concentration assessment in adults with purulent, bacterial meningoencephalitis.
Humans Interleukin-6 Biomarkers Prognosis Female Adult Male Ciliary Neurotrophic Factor Meningoencephalitis Severity of Illness Index Ferritins Meningitis, Bacterial
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Interleukin-6 and interleukin-8 in diagnosing neonatal septicemia.

Journal of biological regulators and homeostatic agents Jan 1, 2016
Neonatal septicemia (NS) is a common cause of death of newborn infants, hence early diagnosis and treatment are of the utmost importance. However, lack of specific clinical symptoms and late detection delay a correct diagnosis. It is therefore of gre...
Male ROC Curve Enzyme-Linked Immunosorbent Assay Area Under Curve Female Infant, Newborn Sensitivity and Specificity Interleukin-8 Neonatal Sepsis Humans Interleukin-6 Prospective Studies
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[Clinical observation on the treatment of phenol burn patients complicated by acute kidney injury with early blood purification].

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns Dec 1, 2015
OBJECTIVE: To observe the clinical effects of early blood purification in the treatment of phenol burn patients complicated by acute kidney injury (AKI).
Interleukin-6 Biomarkers Acute Kidney Injury Severity of Illness Index Humans Burns, Chemical Interleukin-10 Phenol Tumor Necrosis Factor-alpha Serum Hemofiltration Enzyme-Linked Immunosorbent Assay Treatment Outcome Wound Healing Phenols
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[Reproduction of a model of "two-hit" sepsis model with complication of pneumonia in rat].

Zhonghua wei zhong bing ji jiu yi xue Oct 1, 2015
OBJECTIVE: To reproduce a clinically relevant "two-hit" model of sepsis complicated by pneumonia and to explore the correlation between "two-hit" and immune state.
Animals Male Sepsis Rats Tumor Necrosis Factor-alpha Interleukin-6 Creatinine Alanine Transaminase Aspartate Aminotransferases Random Allocation Spleen Blood Urea Nitrogen Receptors, Tumor Necrosis Factor, Type I Pneumonia Rats, Sprague-Dawley HMGB1 Protein Disease Models, Animal Interleukin-1beta Apoptosis Transforming Growth Factor beta1
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