AIMC Topic: Kidney

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Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning.

PloS one
INTRODUCTION: Lupus nephritis (LN) is one of the most frequent and serious organic manifestations of systemic lupus erythematosus (SLE). Autophagy, a new form of programmed cell death, has been implicated in a variety of renal diseases, but the relat...

Machine-learning model based on ultrasomics for non-invasive evaluation of fibrosis in IgA nephropathy.

European radiology
OBJECTIVES: To develop and validate an ultrasomics-based machine-learning (ML) model for non-invasive assessment of interstitial fibrosis and tubular atrophy (IF/TA) in patients with IgA nephropathy (IgAN).

Machine learning-driven Raman spectroscopy: A novel approach to lipid profiling in diabetic kidney disease.

Nanomedicine : nanotechnology, biology, and medicine
Diabetes mellitus is a chronic metabolic disease that increasingly affects people every year. It is known that with its progression and poor management, metabolic changes can lead to organ dysfunctions, including kidneys. The study aimed to combine R...

Challenges in standardizing preimplantation kidney biopsy assessments and the potential of AI-Driven solutions.

Current opinion in nephrology and hypertension
PURPOSE OF REVIEW: This review explores the variability in preimplantation kidney biopsy processing methods, emphasizing their impact on histological interpretation and allocation decisions driven by biopsy findings. With the increasing use of artifi...

Assessing donor kidney function: the role of CIRBP in predicting delayed graft function post-transplant.

Frontiers in immunology
INTRODUCTION: Delayed graft function (DGF) shortens the survival time of transplanted kidneys and increases the risk of rejection. Current methods are inadequate in predicting DGF. More precise tools are required to assess kidney suitability for tran...

Comparative analysis of kidney function prediction: traditional statistical methods vs. deep learning techniques.

Clinical and experimental nephrology
BACKGROUND: Chronic kidney disease (CKD) represents a significant public health challenge, with rates consistently on the rise. Enhancing kidney function prediction could contribute to the early detection, prevention, and management of CKD in clinica...

Exploring the subtle and novel renal pathological changes in diabetic nephropathy using clustering analysis with deep learning.

Scientific reports
To decrease the number of chronic kidney disease (CKD), early diagnosis of diabetic kidney disease is required. We performed invariant information clustering (IIC)-based clustering on glomerular images obtained from nephrectomized kidneys of patients...

Leveraging explainable AI and large-scale datasets for comprehensive classification of renal histologic types.

Scientific reports
Recently, as the number of cancer patients has increased, much research is being conducted for efficient treatment, including the use of artificial intelligence in genitourinary pathology. Recent research has focused largely on the classification of ...

The effect of renal function on the clinical outcomes and management of patients hospitalized with hyperglycemic crises.

Frontiers in endocrinology
BACKGROUND: The global prevalence of diabetes has been rising rapidly in recent years, leading to an increase in patients experiencing hyperglycemic crises like diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). Patients with imp...

Machine learning assisted classification RASAR modeling for the nephrotoxicity potential of a curated set of orally active drugs.

Scientific reports
We have adopted the classification Read-Across Structure-Activity Relationship (c-RASAR) approach in the present study for machine-learning (ML)-based model development from a recently reported curated dataset of nephrotoxicity potential of orally ac...