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Kidney

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Clinicopathological features for the prediction of immunosuppressive treatment responses in sarcoidosis-related kidney involvement: a single-center retrospective study.

Turkish journal of medical sciences
BACKGROUND/AIM: Sarcoidosis is a multisystem disorder that affects many organs, including the kidneys. This single-center retrospective study investigated the clinical, pathological, and laboratory findings of patients with kidney sarcoidosis who wer...

Influence of renal function on blood pressure control and outcome in thrombolyzed patients after acute ischemic stroke: analysis of the ENCHANTED trial.

Frontiers in endocrinology
BACKGROUND: The effect of renal impairment in patients who receive intravenous thrombolysis for acute ischemic stroke (AIS) is unclear. We aimed to determine the associations of renal impairment and clinical outcomes and any modification of the effec...

Unveiling the intricate interplay: Exploring biological bridges between renal ischemia-reperfusion injury and T cell-mediated immune rejection in kidney transplantation.

PloS one
UNLABELLED: Although the link between ischemia-reperfusion injury (IRI) and T cell-mediated rejection (TCMR) in kidney transplantation (KT) is well known, the mechanism remains unclear. We investigated essential genes and biological processes involve...

Multi-stain deep learning prediction model of treatment response in lupus nephritis based on renal histopathology.

Kidney international
The response of the kidney after induction treatment is one of the determinants of prognosis in lupus nephritis, but effective predictive tools are lacking. Here, we sought to apply deep learning approaches on kidney biopsies for treatment response p...

A novel automated method for comprehensive renal cast quantification from rat kidney sections using QuPath.

American journal of physiology. Renal physiology
The presence of tubular casts within the kidney serves as an important feature when assessing the degree of renal injury. Quantification of renal tubular casts has been historically difficult due to varying cast morphologies, protein composition, and...

Interpretable Deep-learning Model Based on Superb Microvascular Imaging for Noninvasive Diagnosis of Interstitial Fibrosis in Chronic Kidney Disease.

Academic radiology
RATIONALE AND OBJECTIVES: To develop an interpretable deep learning (XDL) model based on superb microvascular imaging (SMI) for the noninvasive diagnosis of the degree of interstitial fibrosis (IF) in chronic kidney disease (CKD).

CNN-Based Kidney Segmentation Using a Modified CLAHE Algorithm.

Sensors (Basel, Switzerland)
This paper presents an enhanced approach to kidney segmentation using a modified CLAHE preprocessing method, aimed at improving image clarity and CNN performance on the KiTS19 dataset. To assess the impact of the modified CLAHE method, we conducted q...

Leveraging explainable AI and large-scale datasets for comprehensive classification of renal histologic types.

Scientific reports
Recently, as the number of cancer patients has increased, much research is being conducted for efficient treatment, including the use of artificial intelligence in genitourinary pathology. Recent research has focused largely on the classification of ...

Machine learning assisted classification RASAR modeling for the nephrotoxicity potential of a curated set of orally active drugs.

Scientific reports
We have adopted the classification Read-Across Structure-Activity Relationship (c-RASAR) approach in the present study for machine-learning (ML)-based model development from a recently reported curated dataset of nephrotoxicity potential of orally ac...