AIMC Topic: Lab-On-A-Chip Devices
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Setting Up a Surface-Enhanced Raman Scattering Database for Artificial-Intelligence-Based Label-Free Discrimination of Tumor Suppressor Genes.
Analytical chemistry
Dec 4, 2018
The quality of input data in deep learning is tightly associated with the ultimate performance of the machine learner. Taking advantage of the unique merits of surface-enhanced Raman scattering (SERS) methodology in the collection and construction of...
Kernel-Based Microfluidic Constriction Assay for Tumor Sample Identification.
ACS sensors
Jul 18, 2018
A high-throughput multiconstriction microfluidic channels device can distinguish human breast cancer cell lines (MDA-MB-231, HCC-1806, MCF-7) from immortalized breast cells (MCF-10A) with a confidence level of ∼81-85% at a rate of 50-70 cells/min bas...
Thread/paper- and paper-based microfluidic devices for glucose assays employing artificial neural networks.
Electrophoresis
May 14, 2018
This paper describes the fabrication of and data collection from two microfluidic devices: a microfluidic thread/paper based analytical device (μTPAD) and 3D microfluidic paper-based analytical device (μPAD). Flowing solutions of glucose oxidase (GOx...
Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.
ACS synthetic biology
Jun 7, 2017
Electrowetting-on-dielectric (EWD) digital microfluidic laboratory-on-a-chip platforms demonstrate excellent performance in automating labor-intensive protocols. When coupled with an on-chip electroporation capability, these systems hold promise for ...
Designing a biochip following multiplex polymerase chain reaction for the detection of Salmonella serovars Typhimurium, Enteritidis, Infantis, Hadar, and Virchow in poultry products.
Journal of food and drug analysis
Mar 7, 2017
Salmonella-contaminated foods, especially poultry-derived foods (eggs, chicken meat), are the major source of salmonellosis. Not only in the European Union (EU), but also in the United States, Japan, and other countries, has salmonellosis been an iss...
Automated, high-throughput serum glycoprofiling platform.
Integrative biology : quantitative biosciences from nano to macro
Jul 20, 2015
Complex carbohydrates are rapidly becoming excellent biomarker candidates because of their high sensitivity to pathological changes. However, the discovery of clinical glycobiomarkers has been slow, due to the scarcity of high-throughput glycoanalyti...
Size Control in the Nanoprecipitation Process of Stable Iodine (¹²⁷I) Using Microchannel Reactor-Optimization by Artificial Neural Networks.
AAPS PharmSciTech
Feb 6, 2015
In this study, nanosuspension of stable iodine ((127)I) was prepared by nanoprecipitation process in microfluidic devices. Then, size of particles was optimized using artificial neural networks (ANNs) modeling. The size of prepared particles was eval...
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Talanta
Nov 1, 2025
Osteosarcoma (OS) calls for early diagnosis to significantly improve patient survival rates. Exosomes hold significant potential as noninvasive biomarkers for the early diagnosis of cancer. Here, we design a microfluidic device to purify and analyze ...
Machine learning classification of quorum sensing-induced bacterial aggregation using flow rate assays on paper chips toward bacterial species identification in potable water sources.
Biosensors & bioelectronics
Sep 15, 2025
Preventing waterborne disease caused by bacteria is especially important in low-resource settings, where skilled personnel and laboratory equipment are scarce. This work reports a straightforward method for classifying bacterial species by monitoring...
Deep Learning-Enhanced Hand-Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The early detection of high-risk human papillomavirus (HR-HPV) is crucial for the assessment and improvement of prognosis in cervical cancer. However, existing PCR-based screening methods suffer from inadequate accessibility, which dampens the enthus...
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