AIMC Topic: Lipocalin-2

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Clinical Significance of Urinary Biomarkers in Patients With Primary Focal Segmental Glomerulosclerosis.

The American journal of the medical sciences Dec 30, 2017
BACKGROUND: Focal segmental glomerulosclerosis (FSGS) is often accompanied with tubulointerstitial lesion. This study aimed to assess the role of urinary biomarkers in predicting tubulointerstitial lesion and treatment response in FSGS patients.
Humans Biomarkers Lipocalin-2 Glomerulosclerosis, Focal Segmental Hepatitis A Virus Cellular Receptor 1 Retinol-Binding Proteins Acetylglucosaminidase Kidney Tubules Female Adult Sensitivity and Specificity Male
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Elevated Plasma Neutrophil Gelatinase-Associated Lipocalin Level as a Risk Factor for Anemia in Patients with Systemic Inflammation.

BioMed research international Dec 29, 2016
Studies on neutrophil gelatinase-associated lipocalin (NGAL) as an iron-regulatory protein are limited. This study investigated the relationships between plasma NGAL levels and indices of anemia in 187 patients with systemic inflammation. Plasma NGAL...
Male Middle Aged Inflammation C-Reactive Protein Iron Lipocalin-2 Anemia Odds Ratio Risk Factors Aged Aged, 80 and over Young Adult Adult Humans Biomarkers Female
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Serum cystatin C and neutrophil gelatinase-associated lipocalin in predicting the severity of coronary artery disease in diabetic patients.

Anatolian journal of cardiology Nov 26, 2015
OBJECTIVE: Cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) are biomarkers of renal functions. We evaluated their roles in predicting the severity of coronary artery disease (CAD).
Humans Cystatin C Lipocalin-2 Coronary Artery Disease Lipocalins Diabetes Complications Cross-Sectional Studies Prospective Studies Male Biomarkers Middle Aged Female Glomerular Filtration Rate Aged Diabetes Mellitus
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Predictive Value of Neutrophil Gelatinase-Associated Lipocalin for Contrast-Induced Acute Kidney Injury After Cardiac Catheterization: A Meta-analysis.

The Canadian journal of cardiology Sep 30, 2015
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) accumulates in cortical tubules in acute kidney injury (AKI) patients, with its levels associated with serum creatinine. However, the predictive value of NGAL level for contrast-induced ac...
Cardiac Catheterization Humans Time Factors Biomarkers Contrast Media Acute Kidney Injury Predictive Value of Tests Sensitivity and Specificity Lipocalin-2
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Sputum Neutrophil Gelatinase-Associated Lipocalin as a Biomarker in Asthma-COPD Overlap.

The Journal of the Association of Physicians of India Sep 1, 2023
BACKGROUND: Asthma COPD overlap (ACO) is a consensus-based phenotype having characteristics of both COPD and asthma. Distinguishing ACO from other diseases is even more important as it is related to low health-related quality of life, augmented exace...
Middle Aged Case-Control Studies Sputum Adult Humans Neutrophils Pulmonary Disease, Chronic Obstructive Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome Biomarkers Lipocalin-2 Asthma Forced Expiratory Volume Female Male Aged
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Enhancing Military Burn- and Trauma-Related Acute Kidney Injury Prediction Through an Automated Machine Learning Platform and Point-of-Care Testing.

Archives of pathology & laboratory medicine Mar 1, 2021
CONTEXT.—: Delayed recognition of acute kidney injury (AKI) results in poor outcomes in military and civilian burn-trauma care. Poor predictive ability of urine output (UOP) and creatinine contribute to the delayed recognition of AKI.
Acute Kidney Injury Female Aged Aged, 80 and over Adult Humans Machine Learning Algorithms Biomarkers Lipocalin-2 Burns Creatinine Military Personnel Wounds and Injuries Male Middle Aged Predictive Value of Tests Point-of-Care Testing
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Increased lipocalin-2 vs reduced oxytocin in relation with adiposity, atherogenicity and hematological indices in metabolic syndrome patients with and without prediabetes.

Bratislavske lekarske listy Jan 1, 2018
OBJECTIVES: The neuropeptide hormone- Oxytocin (OXT) and glycoprotein Lipocalin-2 (LCN-2) are strongly associated with cardiometabolic risks of insulin resistance in metabolic syndrome (MetS) and prediabetes (preDM).
Waist Circumference Adiposity Prediabetic State Body Mass Index Humans Metabolic Syndrome Cross-Sectional Studies Lipocalin-2 Oxytocin
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Structural Comparison of Gene Relevance Networks for Breast Cancer Tissues in Different Grades.

Combinatorial chemistry & high throughput screening Jan 1, 2016
BACKGROUND: The breast is an important biological system of human with two distinct states, i.e. normal and tumoral. Research on breast cancer could be based on systematic modeling to contrast the system structures of these two states.
Gene Regulatory Networks Support Vector Machine Lipocalin-2 ErbB Receptors ras Proteins Genes, Neoplasm Proto-Oncogene Proteins c-fos ZAP-70 Protein-Tyrosine Kinase bcl-2 Homologous Antagonist-Killer Protein Humans Female Breast Neoplasms
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Neutrophil Gelatinase-Associated Lipocalin as an Early Sign of Diabetic Kidney Injury in Children.

Journal of clinical research in pediatric endocrinology Dec 1, 2015
OBJECTIVE: There is some evidence indicating that histopathological changes in type 1 diabetes mellitus (T1DM) emerge before onset of microalbuminuria. The aim of our study was to determine whether urine neutrophil gelatinase-associated lipocalin (NG...
Child Diabetic Nephropathies Diabetes Mellitus, Type 1 Acute-Phase Proteins Albuminuria Lipocalin-2 Lipocalins Proto-Oncogene Proteins Humans Female Male Adolescent
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The effect of anaesthetic management on neutrophil gelatinase associated lipocalin (NGAL) levels after robotic surgical oncology.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology Jan 1, 2015
PURPOSE: The main objective of this study was to compare the effect of two anaesthetic techniques (general vs combined) on plasma levels of NGAL (Neutrophil Gelatinase Associated Lipocalin) after robotic urogenital oncosurgery. The secondary objectiv...
Aged Male Middle Aged Incidence Time Factors Prospective Studies Biomarkers Acute Kidney Injury Female Anesthesia, General Lipocalin-2 Surgery, Computer-Assisted Creatinine Anesthesia, Epidural Treatment Outcome Longitudinal Studies Acute-Phase Proteins Robotics Humans Urogenital Neoplasms Urologic Surgical Procedures Gynecologic Surgical Procedures Lipocalins Romania Proto-Oncogene Proteins
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