AIMC Topic: Liposomes
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Lipid nanoparticle (LNP) mediated mRNA delivery in neurodegenerative diseases.
Journal of controlled release : official journal of the Controlled Release Society
May 10, 2025
Neurodegenerative diseases (NDD) are characterized by the progressive loss of neurons and the impairment of cellular functions. Messenger RNA (mRNA) has emerged as a promising therapy for treating NDD, as it can encode missing or dysfunctional protei...
Predicting Calcein Release from Ultrasound-Targeted Liposomes: A Comparative Analysis of Random Forest and Support Vector Machine.
Technology in cancer research & treatment
Jan 1, 2024
OBJECTIVE: This study presents a comparative analysis of RF and SVM for predicting calcein release from ultrasound-triggered, targeted liposomes under varied low-frequency ultrasound (LFUS) power densities (6.2, 9, and 10 mW/cm).
Understanding the Manufacturing Process of Lipid Nanoparticles for mRNA Delivery Using Machine Learning.
Chemical & pharmaceutical bulletin
Jan 1, 2024
Lipid nanoparticles (LNPs), used for mRNA vaccines against severe acute respiratory syndrome coronavirus 2, protect mRNA and deliver it into cells, making them an essential delivery technology for RNA medicine. The LNPs manufacturing process consists...
Improvement of solubility and dissolution of ebastine by fabricating phosphatidylcholine/ bile salt bilosomes.
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
Although ebastine (EBT) can impede histamine-induced skin allergic reaction and persuade long acting selective H1 receptor antagonistic effects but its poor water solubility circumscribed its clinical application. The main objective of this research ...
ACTIVITY OF BLACKCURRANT AND CHOKEBERRY EXTRACTS AND TWO MAJOR CYANIDIN GLYCOSIDES AGAINST LIPID MEMBRANE OXIDATION AND THEIR BINDING PROPERTIES TO ALBUMIN.
Acta poloniae pharmaceutica
Mar 1, 2017
The purpose of this study was to explain how extracts from chokeberry and blackcurrant interact with the lipid phase of biological membrane and with human albumin - the main protein of blood. Aiming at better understanding of the observed biological ...
[Preparation of Baicalein Liposome-Lyophilized Powder and Its Pharmacokinetics Study].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Nov 1, 2015
OBJECTIVE: To prepare baicalein liposome-lyophilized powder, and to investigate the particle size distribution, encapsulation efficiency, stability, in vitro release and in vivo pharmacokirietics in rats. METHODs: Baicalein liposome was prepared by t...
Ultrasound-guided subcostal transversus abdominis plane infiltration with liposomal bupivacaine for patients undergoing robotic-assisted hysterectomy: a retrospective study.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Jun 1, 2015
OBJECTIVE: We sought to determine the effect of a subcostal transversus abdominis plane (TAP) block with liposomal bupivacaine on postoperative maximal pain score and length of hospital stay among women undergoing robotic-assisted hysterectomy.
Paclitaxel-loaded niosomes for intravenous administration: pharmacokinetics and tissue distribution in rats.
Turkish journal of medical sciences
Jan 1, 2015
BACKGROUND/AIM: The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats.
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