AIMC Topic: Lung Neoplasms

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Prediction of Lymph Node Metastasis in Lung Cancer Using Deep Learning of Endobronchial Ultrasound Images With Size on CT and PET-CT Findings.

Respirology (Carlton, Vic.)
BACKGROUND AND OBJECTIVE: Echo features of lymph nodes (LNs) influence target selection during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). This study evaluates deep learning's diagnostic capabilities on EBUS images f...

Machine learning identifies clinical tumor mutation landscape pathways of resistance to checkpoint inhibitor therapy in NSCLC.

Journal for immunotherapy of cancer
BACKGROUND: Immune checkpoint inhibitors (CPIs) have revolutionized cancer therapy for several tumor indications. However, a substantial fraction of patients treated with CPIs derive no benefit or have short-lived responses to CPI therapy. Identifyin...

A feasibility study of lung tumor segmentation on kilo-voltage radiographic images with transfer learning: Toward tumor motion tracking in radiotherapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To segment the lung tumor on kilo-voltage X-ray radiographic images acquired during treatment toward the markerless lung tumor tracking.

Metastatic Lung Lesion Changes in Follow-up Chest CT: The Advantage of Deep Learning Simultaneous Analysis of Prior and Current Scans With SimU-Net.

Journal of thoracic imaging
PURPOSE: Radiological follow-up of oncology patients requires the detection of metastatic lung lesions and the quantitative analysis of their changes in longitudinal imaging studies. Our aim was to evaluate SimU-Net, a novel deep learning method for ...

Identification of potential biomarkers for lung cancer using integrated bioinformatics and machine learning approaches.

PloS one
Lung cancer is one of the most common cancer and the leading cause of cancer-related death worldwide. Early detection of lung cancer can help reduce the death rate; therefore, the identification of potential biomarkers is crucial. Thus, this study ai...

Development and evaluation of a multivariable prediction model for overall survival in advanced stage pulmonary carcinoid using machine learning.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Evidence is limited on whether patients with advanced pulmonary carcinoid (APC) benefit from comprehensive pulmonary resection (CPR), chemotherapy, or radiotherapy. Existing prognostic models for APC are limited and do not guide treatment...

Histological proven AI performance in the UKLS CT lung cancer screening study: Potential for workload reduction.

European journal of cancer (Oxford, England : 1990)
PURPOSE: Artificial intelligence (AI) could reduce lung cancer screening computer tomography (CT)-reading workload if used as a first-reader, ruling-out negative CT-scans at baseline. Evidence is lacking to support AI performance when compared to gol...

The feasibility and cost-effectiveness of implementing mobile low-dose computed tomography with an AI-based diagnostic system in underserved populations.

BMC cancer
BACKGROUND: Low-dose computed tomography (LDCT) significantly increases early detection rates of lung cancer and reduces lung cancer-related mortality by 20%. However, many significant screening barriers remain. This study conduct an initial feasibil...

A PET/CT-based 3D deep learning model for predicting spread through air spaces in stage I lung adenocarcinoma.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: This study evaluates a three-dimensional (3D) deep learning (DL) model based on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for predicting the preoperative status of spread through air spa...

Optimizing Bi-LSTM networks for improved lung cancer detection accuracy.

PloS one
Lung cancer remains a leading cause of cancer-related deaths worldwide, with low survival rates often attributed to late-stage diagnosis. To address this critical health challenge, researchers have developed computer-aided diagnosis (CAD) systems tha...