The escalating global burden of chronic kidney disease (CKD), particularly end-stage renal disease (ESRD), has intensified reliance on hemodialysis (HD), imposing substantial financial and operational burdens on healthcare systems and patients. Intra...
BACKGROUND: Variants of uncertain significance (VUS) represent a major diagnostic challenge in the interpretation of genetic testing results, particularly in the context of inborn errors of immunity such as severe combined immunodeficiency (SCID). Th...
This study aimed to develop a predictive model and construct a graded nomogram to estimate the risk of severe acute kidney injury (AKI) in patients without preexisting kidney dysfunction undergoing liver transplantation (LT). Patients undergoing LT b...
This study aimed to investigate the release and attenuation mechanisms of Cr(VI) in a shallow aquifer system and evaluate the remediation performance of a permeable reactive barrier (PRB) in central China. A hydrogeochemical and machine learning fram...
Mass-based fingerprinting can characterize microorganisms; however, expansion of these methods to predict specific gene functions is lacking. Therefore, mass fingerprinting was developed to functionally profile a yeast knockout library. Matrix-assist...
Colorectal cancer (CRC) is a major global health challenge due to its high incidence, mortality, and low rate of early detection. Early diagnosis, targeting precancerous lesions (advanced adenomas) and early stage CRC (Tis and T1), is critical for im...
Journal of chemical information and modeling
Sep 10, 2025
The calculation of the highest occupied molecular orbital-lowest unoccupied molecular orbital (HOMO-LUMO) gap for chemical molecules is computationally intensive using quantum mechanics (QM) methods, while experimental determination is often costly a...
Developing intelligent robots with integrated sensing capabilities is critical for advanced manufacturing, medical robots, and embodied intelligence. Existing robotic sensing technologies are limited to recording of acceleration, driving torque, pres...
BACKGROUND: Total knee and hip arthroplasty (TKA and THA) are among the most performed elective procedures. Rising demand and the resource-intensive nature of these procedures have contributed to longer wait times despite significant health care inve...
BACKGROUND: Cirrhosis is a leading cause of noncancer deaths in gastrointestinal diseases, resulting in high hospitalization and readmission rates. Early identification of high-risk patients is vital for proactive interventions and improving health c...
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