AIMC Topic: Machine Learning

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Impact of pre-analytical variables on deep learning accuracy in histopathology.

Histopathology
AIMS: Machine learning (ML) binary classification in diagnostic histopathology is an area of intense investigation. Several assumptions, including training image quality/format and the number of training images required, appear to be similar in many ...

Design of Natural-Product-Inspired Multitarget Ligands by Machine Learning.

ChemMedChem
A virtual screening protocol based on machine learning models was used to identify mimetics of the natural product (-)-galantamine. This fully automated approach identified eight compounds with bioactivities on at least one of the macromolecular targ...

Machine learning for prediction of sudden cardiac death in heart failure patients with low left ventricular ejection fraction: study protocol for a retroprospective multicentre registry in China.

BMJ open
INTRODUCTION: Left ventricular ejection fraction (LVEF) ≤35%, as current significant implantable cardioverter-defibrillator (ICD) indication for primary prevention of sudden cardiac death (SCD) in heart failure (HF) patients, has been widely recognis...

HOME: a histogram based machine learning approach for effective identification of differentially methylated regions.

BMC bioinformatics
BACKGROUND: The development of whole genome bisulfite sequencing has made it possible to identify methylation differences at single base resolution throughout an entire genome. However, a persistent challenge in DNA methylome analysis is the accurate...

Machine learning analysis of MRI-derived texture features to predict placenta accreta spectrum in patients with placenta previa.

Magnetic resonance imaging
PURPOSE: To evaluate whether a machine learning (ML) analysis employing MRI-derived texture analysis (TA) features could be useful in assessing the presence of placenta accreta spectrum (PAS) in patients with placenta previa (PP). The hypothesis is t...

Machine learning prediction of nanoparticle in vitro toxicity: A comparative study of classifiers and ensemble-classifiers using the Copeland Index.

Toxicology letters
Nano-Particles (NPs) are well established as important components across a broad range of products from cosmetics to electronics. Their utilization is increasing with their significant economic and societal potential yet to be fully realized. Inroads...

Automating Ischemic Stroke Subtype Classification Using Machine Learning and Natural Language Processing.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVE: The manual adjudication of disease classification is time-consuming, error-prone, and limits scaling to large datasets. In ischemic stroke (IS), subtype classification is critical for management and outcome prediction. This study sought to...

Neo-adjuvant chemoradiotherapy response prediction using MRI based ensemble learning method in rectal cancer patients.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
OBJECTIVES: The aim of this study was to investigate and validate the performance of individual and ensemble machine learning models (EMLMs) based on magnetic resonance imaging (MRI) to predict neo-adjuvant chemoradiation therapy (nCRT) response in r...

A Hybridized ELM for Automatic Micro Calcification Detection in Mammogram Images Based on Multi-Scale Features.

Journal of medical systems
Detection of masses and micro calcifications are a stimulating task for radiologists in digital mammogram images. Radiologists using Computer Aided Detection (CAD) frameworks to find the breast lesion. Micro calcification may be the early sign of bre...