Alga toxins have recently emerged as environmental risk factors to multiple human health issues. Mitochondrial toxicity is an essential element in the field of ecotoxicology, it is necessary to screen and manage mitochondrial toxicants from common al...
Journal of chemical information and modeling
Apr 11, 2025
The pharmaceutical industry faces challenges in developing efficient and cost-effective drug delivery systems. Among various applications, antibody-drug conjugates (ADCs) stand out by combining cytotoxic or bioactive agents with monoclonal antibodies...
The expression levels of microRNAs (miRNAs) are strongly linked to cancer progression, making them promising biomarkers for cancer detection. Enzyme-free signal amplification DNA circuits have facilitated the detection of low-abundance miRNAs. Howeve...
Persistent organic pollutants (POPs), including PCDD/Fs, PCBs, and PBDEs, are major environmental and food safety concerns due to their bioaccumulative and toxic properties. However, comprehensive research on the concentrations and influencing factor...
Research investigating the prenatal chemical exposome and child neurodevelopment has typically focused on a limited number of chemical exposures and controlled for sociodemographic factors and maternal mental health. Emerging machine learning approac...
In this study, we introduce PFASorptionML, a novel machine learning (ML) tool developed to predict solid-liquid distribution coefficients () for per- and polyfluoroalkyl substances (PFAS) in soils. Leveraging a data set of 1,274 entries for PFAS in ...
BACKGROUND: The global increase in life expectancy has not shown a similar rise in healthy life expectancy. Accurate assessment of biological aging is crucial for mitigating diseases and socioeconomic burdens associated with aging. Current biological...
BMC medical informatics and decision making
Apr 11, 2025
BACKGROUND: Malaria, an infectious disease caused by protozoan parasites belonging to the Plasmodium genus, remains a significant public health challenge, with African regions bearing the heaviest burden. Machine learning techniques have shown great ...
Non-alcoholic fatty liver disease (NAFLD) affects about 25% of adults worldwide. Its advanced form, non-alcoholic steatohepatitis (NASH), is a major cause of liver fibrosis, but there are no non-invasive tests for diagnosing or preventing it. In our ...
Over the past several decades, there has been a significant increase in the number of breast cancer patients. Among the four subtypes of breast cancer, Her2-positive breast cancer is one of the most aggressive breast cancers. In this study, we screen...
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