AIMC Topic: Machine Learning

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Unveiling the role of PANoptosis-related genes in breast cancer: an integrated study by multi-omics analysis and machine learning algorithms.

Breast cancer research and treatment
BACKGROUND: The heterogeneity of breast cancer (BC) necessitates the identification of novel subtypes and prognostic models to enhance patient stratification and treatment strategies. This study aims to identify novel BC subtypes based on PANoptosis-...

Machine learning to predict stroke risk from routine hospital data: A systematic review.

International journal of medical informatics
PURPOSE: Stroke remains a leading cause of morbidity and mortality. Despite this, current risk stratification tools such as CHADS-VASc and QRISK3 are of limited accuracy, particularly in those without a diagnosis of atrial-fibrillation. Hence, there ...

EHR-ML: A data-driven framework for designing machine learning applications with electronic health records.

International journal of medical informatics
OBJECTIVE: The healthcare landscape is experiencing a transformation with the integration of Artificial Intelligence (AI) into traditional analytic workflows. However, its integration faces challenges resulting in a crisis of generalisability. Key ob...

Predictive models of clinical outcome of endovascular treatment for anterior circulation stroke using machine learning.

Journal of neuroscience methods
BACKGROUND AND PURPOSE: Mechanical Thrombectomy (MT) has recently become the standard of care for anterior circulation stroke with large vessel occlusion, but predictive factors of successful MT are still not clearly defined. To tailor treatment indi...

Multimodal learning for mapping genotype-phenotype dynamics.

Nature computational science
How complex phenotypes emerge from intricate gene expression patterns is a fundamental question in biology. Integrating high-content genotyping approaches such as single-cell RNA sequencing and advanced learning methods such as language models offers...

Machine learning reveals the dynamic importance of accessory sequences for outbreak clustering.

mBio
UNLABELLED: Bacterial typing at whole-genome scales is now feasible owing to decreasing costs in high-throughput sequencing and the recent advances in computation. The unprecedented resolution of whole-genome typing is achieved by genotyping the vari...

Development and validation of machine learning-based prediction model for central venous access device-related thrombosis in children.

Thrombosis research
BACKGROUND: Identifying independent risk factors and implementing high-quality assessment tools for early detection of patients at high risk of central venous access device (CVAD)-related thrombosis (CRT) plays a critical role in delivering timely pr...

Prediction of mortality in heart failure by machine learning. Comparison with statistical modeling.

European journal of internal medicine
BACKGROUND: Assessing the relative performance of machine learning (ML) methods and conventional statistical methods in predicting prognosis in heart failure (HF) still remains a challenging research field.

On QSPR analysis of glaucoma drugs using machine learning with XGBoost and regression models.

Computers in biology and medicine
Glaucoma is an irreversible, progressive, degenerative eye disorder arising because of increased intraocular pressure, resulting in eventual vision loss if untreated. The QSPR relates, mathematically, by employing various algorithms, a specified prop...