AIMC Topic: Macrophages
Clear Filters Showing 21 to 30 of 95 articles
Exploring the role of oxidative stress in carotid atherosclerosis: insights from transcriptomic data and single-cell sequencing combined with machine learning.
Biology direct
Jan 29, 2025
BACKGROUND: Carotid atherosclerotic plaque is the primary cause of cardiovascular and cerebrovascular diseases. It is closely related to oxidative stress and immune inflammation. This bioinformatic study was conducted to identify key oxidative stress...
Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn's disease by bioinformatics analysis and machine learning.
Scientific reports
Jan 27, 2025
Crohn's disease (CD) is a chronic inflammatory bowel disease with an unknown etiology. Ubiquitination plays a significant role in the pathogenesis of CD. This study aimed to explore the functional roles of ubiquitination-related genes in CD. Differen...
Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing.
Frontiers in immunology
Jan 3, 2025
BACKGROUND: Anti-citrullinated peptide antibodies (ACPA)-negative (ACPA-) rheumatoid arthritis (RA) presents significant diagnostic and therapeutic challenges due to the absence of specific biomarkers, underscoring the need to elucidate its distincti...
A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology.
PloS one
Dec 31, 2024
The motility of macrophages in response to microenvironment stimuli is a hallmark of innate immunity, where macrophages play pro-inflammatory or pro-reparatory roles depending on their activation status during wound healing. Cell size and shape have ...
Identification and verification of the optimal feature genes of ferroptosis in thyroid-associated orbitopathy.
Frontiers in immunology
Dec 13, 2024
BACKGROUND: Thyroid-associated orbitopathy (TAO) is an autoimmune inflammatory disorder of the orbital adipose tissue, primarily causing oxidative stress injury and tissue remodeling in the orbital connective tissue. Ferroptosis is a form of programm...
Machine learning models for quantitatively prediction of toxicity in macrophages induced by metal oxide nanoparticles.
Chemosphere
Dec 10, 2024
As nanotechnology advances, metal oxide nanoparticles (MeONPs) increasingly come into contact with humans. The inhaled MeONPs cannot be effectively cleared by cilia or lung mucus. In the last decade, potential immune toxicity arising from exposure to...
Identification of CCR7 and CBX6 as key biomarkers in abdominal aortic aneurysm: Insights from multi-omics data and machine learning analysis.
IET systems biology
Nov 27, 2024
Abdominal aortic aneurysm (AAA) is a severe vascular condition, marked by the progressive dilation of the abdominal aorta, leading to rupture if untreated. The objective of this study was to identify key biomarkers and decipher the immune mechanisms ...
Identification of immune patterns in idiopathic pulmonary fibrosis patients driven by PLA2G7-positive macrophages using an integrated machine learning survival framework.
Scientific reports
Sep 27, 2024
Patients with advanced idiopathic pulmonary fibrosis (IPF), a complex and incurable lung disease with an elusive pathology, are nearly exclusive candidates for lung transplantation. Improved identification of patient subtypes can enhance early diagno...
Deep learning reveals a damage signalling hierarchy that coordinates different cell behaviours driving wound re-epithelialisation.
Development (Cambridge, England)
Sep 24, 2024
One of the key tissue movements driving closure of a wound is re-epithelialisation. Earlier wound healing studies describe the dynamic cell behaviours that contribute to wound re-epithelialisation, including cell division, cell shape changes and cell...
Probing Nanotopography-Mediated Macrophage Polarization via Integrated Machine Learning and Combinatorial Biophysical Cue Mapping.
ACS nano
Sep 3, 2024
Inflammatory responses, leading to fibrosis and potential host rejection, significantly hinder the long-term success and widespread adoption of biomedical implants. The ability to control and investigated macrophage inflammatory responses at the impl...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 32021
- Neural Networks, Computer 30231
- Algorithms 27405
- Deep Learning 26912
- Artificial Intelligence 24844
- Robotics 13389
- Image Processing, Computer-Assisted 9738
- Retrospective Studies 9346
- Magnetic Resonance Imaging 6347
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4866
- Support Vector Machine 4771
- Computational Biology 4333
- Brain 4129
- Computer Simulation 3935
Recent Journals
- Scientific reports 6800
- Sensors (Basel, Switzerland) 4794
- PloS one 4210
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1916
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1172
- Journal of chemical information and modeling 1066
- Nature communications 1047
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 874
- Journal of medical Internet research 864
- Briefings in bioinformatics 853