Immunotherapy has become a cornerstone in the treatment of advanced gastric cancer (GC). However, identifying reliable predictive biomarkers remains a considerable challenge. This study demonstrates the potential of integrating multimodal baseline da...
Clinica chimica acta; international journal of clinical chemistry
Jul 15, 2025
OBJECTIVE: Immunoglobulin D (IgD) myeloma is a rare subtype of multiple myeloma (MM), comprising approximately 1 %-2 % of all MM cases. Owing to the diminished levels of IgD in serum, IgD MM manifests as subtle M protein spikes in routine serum elect...
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Jul 15, 2025
BACKGROUND: Survival of patients with high-risk hepatoblastoma remains low, and early identification of high-risk hepatoblastoma is critical.
We aimed to explore the metabolic dysregulations and diagnostic biomarkers for post-traumatic deep venous thrombosis (pt-DVT) in hypertensive (HPT) patients after fracture. An untargeted ultraperformance liquid chromatography-mass spectrometry-based ...
RATIONALE: Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in COPD risk. COPD occurrence in non-smokers with AAT deficiency (AATD) suggests that inflammatory processes may contribute to COPD risk indepe...
BMC medical informatics and decision making
Jul 15, 2025
PURPOSE: Accurate identification of bone marrow invasion (BMI) is critical for determining the prognosis of and treatment strategies for lymphoma. Although bone marrow biopsy (BMB) is the current gold standard, its invasive nature and sampling errors...
BMC medical informatics and decision making
Jul 15, 2025
BACKGROUND: Drug-induced immune thrombocytopenia (DITP) is a rare but potentially life-threatening adverse drug reaction, often underrecognized due to its nonspecific presentation and the lack of real-time diagnostic tools. Early identification of at...
BMC medical informatics and decision making
Jul 15, 2025
BACKGROUND: Hemorrhage is a prevalent and critical condition in the intensive care unit (ICU), characterized by high incidence, elevated mortality rates, and substantial therapeutic challenges. Accurate prediction of mortality in patients with hemorr...
BACKGROUND: Artificial intelligence (AI) is reshaping healthcare, yet its integration into medical education remains limited. This study assesses undergraduate healthcare students' knowledge and perceptions of AI, its applications, challenges, and th...
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