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Deep Learning-Based Fully Automated Aortic Valve Leaflets and Root Measurement From Computed Tomography Images - A Feasibility Study.

Circulation journal : official journal of the Japanese Circulation Society
BACKGROUND: The aim of this study was to retrain our existing deep learning-based fully automated aortic valve leaflets/root measurement algorithm, using computed tomography (CT) data for root dilatation (RD), and assess its clinical feasibility.

Porous-Structure Flexible Muscle Sensor for Monitoring Muscle Function and Mass.

ACS sensors
Muscle function and composition are important indicators of age-related health. However, current assessment methods are often complex and expensive, making the early detection of related problems difficult. Therefore, developing a cost-effective and ...

Toxicity of nanoplastics: machine learning combined with meta-analysis.

Nanoscale horizons
Nanoplastics (NPs) are widespread in ecosystems, and their biohazards are of increasing concern. The hazards posed by NPs to aquatic and terrestrial plants as well as to aquatic animals have been extensively studied; however, their impact on mammals ...

Diagnostic report generation for macular diseases by natural language processing algorithms.

The British journal of ophthalmology
AIMS: To investigate rule-based and deep learning (DL)-based methods for the automatically generating natural language diagnostic reports for macular diseases.

CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.

Free radical biology & medicine
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of ef...

Integration of multi-omics data and machine learning to identify antioxidant biomarkers in type 1 diabetes.

Free radical biology & medicine
The identification of biomarkers for early diagnosis and monitoring the progression of Type 1 Diabetes (T1DM) is essential for improving disease management. This study integrates multi-omics data with machine learning to identify antioxidant stress p...

Tribulus terrestris L. Extract Alleviates Atherosclerosis by Suppressing TNF-α-Mediated Macrophage Inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Atherosclerosis (AS) is a major contributor to cardiovascular disease. In traditional Chinese medicine, Tribulus terrestris L., or Baijili (BJL), has shown therapeutic effects on inflammation and cardiovascular issues. Our prior research indicated th...

A preliminary attempt to harmonize using physics-constrained deep neural networks for multisite and multiscanner MRI datasets (PhyCHarm).

NeuroImage
In magnetic resonance imaging (MRI), variations in scan parameters and scanner specifications can result in differences in image appearance. To minimize these differences, harmonization in MRI has been suggested as a crucial image processing techniqu...

The melanoma MEGA-study: Integrating proteogenomics, digital pathology, and AI-analytics for precision oncology.

Journal of proteomics
Melanoma remains the most aggressive form of skin cancer, characterized by high metastatic potential, genetic heterogeneity, and resistance to conventional therapies. The Melanoma MEGA-Study is a multi-center initiative designed to address these clin...

Multimodal personalization of transcranial direct current stimulation for modulation of sensorimotor integration.

NeuroImage
Transcranial direct current stimulation (tDCS) for the modulation of smooth pursuit eye movements provides an ideal model for investigating sensorimotor integration. Within neural networks subserving smooth pursuit, visual area V5 is a core hub where...