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Machine learning based radiomic models outperform clinical biomarkers in predicting outcomes after immunotherapy for hepatocellular carcinoma.

Journal of hepatology
BACKGROUND & AIMS: Atezolizumab plus bevacizumab (A/B) is a first-line therapy for unresectable hepatocellular carcinoma (HCC). Only a small proportion of patients respond to treatment. This study integrated radiomic and clinical data derived from ro...

Exploring the potential of large language models to understand interpersonal emotion regulation strategies from narratives.

Emotion (Washington, D.C.)
Interpersonal emotion regulation involves using diverse strategies to influence others' emotions, commonly assessed with questionnaires. However, this method may be less effective for individuals with limited literacy or introspection skills. To addr...

Multi-modal multi-task deep neural networks for sleep disordered breathing assessment using cardiac and audio signals.

International journal of medical informatics
BACKGROUND AND OBJECTIVE: Sleep disordered breathing (SDB) is one of the most common sleep disorders and has short-term consequences for daytime functioning while being a risk factor for several conditions, such as cardiovascular disease. Polysomnogr...

Combined peritumoral radiomics and clinical features predict 12-month progression free survival in glioblastoma.

Journal of neuro-oncology
PURPOSE: Analyzing post-treatment MRIs from glioblastoma patients can be challenging due to similar radiological presentations of disease progression and treatment effects. Identifying radiomics features (RFs) revealing progressive glioblastoma can c...

Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.

Epilepsy & behavior : E&B
BACKGROUND & OBJECTIVE: Alzheimer's Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, whether AD and epilepsy share pathophysiological changes remains poorly defined. In this study, we levera...

Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria.

Microbiology spectrum
UNLABELLED: Antimicrobial resistance is an escalating global health crisis, underscoring the urgent need for timely and targeted therapies to ensure effective clinical treatment. We developed a machine learning model based on metagenomic next-generat...

Joint resting state and structural networks characterize pediatric bipolar patients compared to healthy controls: a multimodal fusion approach.

NeuroImage
Pediatric bipolar disorder (PBD) is a highly debilitating condition, characterized by alternating episodes of mania and depression, with intervening periods of remission. Limited information is available about the functional and structural abnormalit...

Assessing the association of multi-environmental chemical exposures on metabolic syndrome: A machine learning approach.

Environment international
Metabolic syndrome (MetS) is a major global public health concern due to its rising prevalence and association with increased risks of cardiovascular disease and type 2 diabetes. Emerging evidence suggests that environmental chemical exposures may pl...

Existential risk narratives about AI do not distract from its immediate harms.

Proceedings of the National Academy of Sciences of the United States of America
There is broad consensus that AI presents risks, but considerable disagreement about the nature of those risks. These differing viewpoints can be understood as distinct narratives, each offering a specific interpretation of AI's potential dangers. On...

Classification of Grades of Subchondral Sclerosis from Knee Radiographic Images Using Artificial Intelligence.

Sensors (Basel, Switzerland)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people worldwide. Subchondral sclerosis is a key indicator of OA. Currently, the diagnosis of subchondral sclerosis is primarily based on radiographic images; however, r...