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Deep Learning-Based Precontrast CT Parcellation for MRI-Free Brain Amyloid PET Quantification.

Clinical nuclear medicine
PURPOSE: This study aimed to develop a deep learning (DL) model for brain region parcellation using CT data from PET/CT scans to enable accurate amyloid quantification in 18 F-FBB PET/CT without relying on high-resolution MRI.

Phase-contrast magnetic resonance imaging-based predictive modelling for surgical outcomes in patients with Chiari malformation type 1 with syringomyelia: a machine learning study.

Clinical radiology
AIM: Prospective outcome prediction plays a crucial role in guiding preoperative decision-making in patients with Chiari malformation type I (CM-Ⅰ) with syringomyelia. Here, we aimed to develop a predictive model for postoperative outcomes in patient...

Individual risk and prognostic value prediction by interpretable machine learning for distant metastasis in neuroblastoma: A population-based study and an external validation.

International journal of medical informatics
PURPOSE: Neuroblastoma (NB) is a childhood malignancy with a poor prognosis and a propensity for distant metastasis (DM). We aimed to establish machine learning (ML) based model to accurately predict risk of DM and prognosis of NB patients with DM.

Development and external validation of a machine learning model to predict the initial dose of vancomycin for targeting an area under the concentration-time curve of 400-600 mg∙h/L.

International journal of medical informatics
PURPOSE: To develop and validate a novel artificial intelligence model for predicting the initial empiric dose of vancomycin, with the aim of achieving an area under the concentration-time curve (AUC) of 400-600 mg∙h/L, using individual clinical data...

DSAM: A deep learning framework for analyzing temporal and spatial dynamics in brain networks.

Medical image analysis
Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional connectivity matrix a...

The impact of the novel CovBat harmonization method on enhancing radiomics feature stability and machine learning model performance: A multi-center, multi-device study.

European journal of radiology
PURPOSE: This study aims to assess whether the novel CovBat harmonization method can further reduce radiomics feature variability from different imaging devices in multi-center studies and improve machine learning model performance compared to the Co...

Enhancing quantitative coronary angiography (QCA) with advanced artificial intelligence: comparison with manual QCA and visual estimation.

The international journal of cardiovascular imaging
Artificial intelligence-based quantitative coronary angiography (AI-QCA) was introduced to address manual QCA's limitations in reproducibility and correction process. The present study aimed to assess the performance of an updated AI-QCA solution (MP...

Spatially resolved transcriptomics and graph-based deep learning improve accuracy of routine CNS tumor diagnostics.

Nature cancer
The diagnostic landscape of brain tumors integrates comprehensive molecular markers alongside traditional histopathological evaluation. DNA methylation and next-generation sequencing (NGS) have become a cornerstone in central nervous system (CNS) tum...