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Metabolic Syndrome

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Increased lipocalin-2 vs reduced oxytocin in relation with adiposity, atherogenicity and hematological indices in metabolic syndrome patients with and without prediabetes.

Bratislavske lekarske listy
OBJECTIVES: The neuropeptide hormone- Oxytocin (OXT) and glycoprotein Lipocalin-2 (LCN-2) are strongly associated with cardiometabolic risks of insulin resistance in metabolic syndrome (MetS) and prediabetes (preDM).

Effect of combined vitamin D administration plus dietary intervention on oxidative stress markers in patients with metabolic syndrome: A pilot randomized study.

Clinical nutrition ESPEN
BACKGROUND: Metabolic syndrome (MetS) patients can have low 25-hydroxyvitamin D 25(OH)VitD levels, which may be associated with increased oxidative stress. There is little data on the effect of 25(OH)VitD administration plus dietary intervention on o...

Prediction models to identify individuals at risk of metabolic syndrome who are unlikely to participate in a health intervention program.

International journal of medical informatics
OBJECTIVES: Since the launch of a nationwide general health check-up and instruction program in Japan in 2008, interest in strategies to improve implementation of the program based on predictive analytics has grown. We investigated the performance of...

High Amounts of Sitting, Low Cardiorespiratory Fitness, and Low Physical Activity Levels: 3 Key Ingredients in the Recipe for Influencing Metabolic Syndrome Prevalence.

American journal of health promotion : AJHP
PURPOSE: Limited research has evaluated the independent and additive associations of moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB), and cardiorespiratory fitness (CRF) with metabolic syndrome, which was the purpose of this st...

Fuzzy logic based risk assessment system giving individualized advice for metabolic syndrome and fatal cardiovascular diseases.

Technology and health care : official journal of the European Society for Engineering and Medicine
In 2005, global cardiovascular diseases caused 30% of deaths in Europe, which is 46% of total deaths for all death groups. Today, according to the International Adult Diabetes Federation, 20% to 25% of the adult population in the world has Metabolic ...

Identifying pre-disease signals before metabolic syndrome in mice by dynamical network biomarkers.

Scientific reports
The establishment of new therapeutic strategies for metabolic syndrome is urgently needed because metabolic syndrome, which is characterized by several disorders, such as hypertension, increases the risk of lifestyle-related diseases. One approach is...

Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection.

Metabolic syndrome and related disorders
We investigated the prevalence and the most relevant features of nonalcoholic steatohepatitis (NASH), a stage of nonalcoholic fatty liver disease, (NAFLD) in which the inflammation of hepatocytes can lead to increased cardiovascular risk, liver fibr...

An unsupervised learning approach to identify novel signatures of health and disease from multimodal data.

Genome medicine
BACKGROUND: Modern medicine is rapidly moving towards a data-driven paradigm based on comprehensive multimodal health assessments. Integrated analysis of data from different modalities has the potential of uncovering novel biomarkers and disease sign...