AIMC Topic: Middle Aged

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A Machine Learning Approach for High-Dimensional Time-to-Event Prediction With Application to Immunogenicity of Biotherapies in the ABIRISK Cohort.

Frontiers in immunology
Predicting immunogenicity for biotherapies using patient and drug-related factors represents nowadays a challenging issue. With the growing ability to collect massive amount of data, machine learning algorithms can provide efficient predictive tools....

Improving energy expenditure estimates from wearable devices: A machine learning approach.

Journal of sports sciences
A means of quantifying continuous, free-living energy expenditure (EE) would advance the study of bioenergetics. The aim of this study was to apply a non-linear, machine learning algorithm (random forest) to predict minute level EE for a range of act...

Multivariate patterns of EEG microstate parameters and their role in the discrimination of patients with schizophrenia from healthy controls.

Psychiatry research
Quasi-stable electrical fields in the EEG, called microstates carry information on the dynamics of large scale brain networks. Using machine learning techniques, we explored whether abnormalities in microstates can be used to classify patients with s...

Multiphase CT-based prediction of Child-Pugh classification: a machine learning approach.

European radiology experimental
BACKGROUND: To evaluate whether machine learning algorithms allow the prediction of Child-Pugh classification on clinical multiphase computed tomography (CT).

Opening the black box of artificial intelligence for clinical decision support: A study predicting stroke outcome.

PloS one
State-of-the-art machine learning (ML) artificial intelligence methods are increasingly leveraged in clinical predictive modeling to provide clinical decision support systems to physicians. Modern ML approaches such as artificial neural networks (ANN...

Application of Generalized Split Linearized Bregman Iteration algorithm for Alzheimer's disease prediction.

Aging
In this paper, we applied a novel method for the detection of Alzheimer's disease (AD) based on a structural magnetic resonance imaging (sMRI) dataset. Specifically, the method involved a new classification algorithm of machine learning, named Genera...

Detecting Abnormal Brain Regions in Schizophrenia Using Structural MRI via Machine Learning.

Computational intelligence and neuroscience
Utilizing neuroimaging and machine learning (ML) to differentiate schizophrenia (SZ) patients from normal controls (NCs) and for detecting abnormal brain regions in schizophrenia has several benefits and can provide a reference for the clinical diagn...

Precise pulmonary scanning and reducing medical radiation exposure by developing a clinically applicable intelligent CT system: Toward improving patient care.

EBioMedicine
BACKGROUND: Interstitial lung disease requires frequent re-examination, which directly causes excessive cumulative radiation exposure. To date, AI has not been applied to CT for enhancing clinical care; thus, we hypothesize AI may empower CT with int...

Deep learning-based cancer survival prognosis from RNA-seq data: approaches and evaluations.

BMC medical genomics
BACKGROUND: Recent advances in kernel-based Deep Learning models have introduced a new era in medical research. Originally designed for pattern recognition and image processing, Deep Learning models are now applied to survival prognosis of cancer pat...

Automatic detection of cortical arousals in sleep and their contribution to daytime sleepiness.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: Significant interscorer variability is found in manual scoring of arousals in polysomnographic recordings (PSGs). We propose a fully automatic method, the Multimodal Arousal Detector (MAD), for detecting arousals.