AIMC Topic: Middle Aged

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Absolute oral bioavailability and pharmacokinetics of canagliflozin: A microdose study in healthy participants.

Clinical pharmacology in drug development
Absolute oral bioavailability of canagliflozin was assessed by simultaneous oral administration with intravenous [(14) C]-canagliflozin microdose infusion in nine healthy men. Pharmacokinetics of canagliflozin, [(14) C]-canagliflozin, and total radio...

Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex.

Neurobiology of disease
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (S...

Robotic single-port hysterectomy, adnexectomy, and lymphadenectomy in endometrial cancer.

Journal of minimally invasive gynecology
STUDY OBJECTIVE: To report the feasibility of performing robotic single-port surgery including pelvic lymphadenectomy in endometrial cancer.

Robotic telepresence versus standardly supervised stroke alert team assessments.

Telemedicine journal and e-health : the official journal of the American Telemedicine Association
BACKGROUND: Telemedicine has created access to emergency stroke care for patients in all communities, regardless of geography. We hypothesized that there is no difference in speed of assessment between vascular neurologist (VN) robotic telepresence a...

A generic support vector machine model for preoperative glioma survival associations.

Radiology
PURPOSE: To develop a generic support vector machine (SVM) model by using magnetic resonance (MR) imaging-based blood volume distribution data for preoperative glioma survival associations and to prospectively evaluate the diagnostic effectiveness of...

Prediction of revascularization after myocardial perfusion SPECT by machine learning in a large population.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
OBJECTIVE: We aimed to investigate if early revascularization in patients with suspected coronary artery disease can be effectively predicted by integrating clinical data and quantitative image features derived from perfusion SPECT (MPS) by machine l...

Robotic and video-assisted thoracic surgery lung segmentectomy for malignant and benign lesions.

Interactive cardiovascular and thoracic surgery
OBJECTIVES: The experience with robotic techniques (RATS) and video-assisted thoracic surgery (VATS) in pulmonary segmentectomy is still limited. We evaluated our prospectively recorded database to compare two different minimally invasive techniques.

Predicting outcome in clinically isolated syndrome using machine learning.

NeuroImage. Clinical
We aim to determine if machine learning techniques, such as support vector machines (SVMs), can predict the occurrence of a second clinical attack, which leads to the diagnosis of clinically-definite Multiple Sclerosis (CDMS) in patients with a clini...

Determining the appropriate amount of anesthetic gas using DWT and EMD combined with neural network.

Journal of medical systems
The spectrum of EEG has been studied to predict the depth of anesthesia using variety of signal processing methods up to date. Those standard models have used the full spectrum of EEG signals together with the systolic-diastolic pressure and pulse va...