Data used to understand knee osteoarthritis (KOA) often involves knee-level, rather than person-level information. Failure to account for the correlation between joints within a person may lead to inaccurate inferences. The aim of this study was to d...
OBJECTIVES: Renal biopsy is the gold standard for the diagnosis of glomerular diseases including membranous nephropathy (MN), however, it faces challenges in accuracy, objectivity, and reproducibility of tissue evaluation. This study aims to develop ...
OBJECTIVE: To construct a predictive model for the reduction in methadone maintenance treatment (MMT) and evaluate the effects of different interventions and other clinical factors on methadone reduction using Shapley additive explanations (SHAP).
BACKGROUND: Accurately assessing the risk stratification of cN0 papillary thyroid carcinoma (PTC) preoperatively aids in making treatment decisions. We integrated preoperative ultrasound and cytological images of patients to develop and validate a mu...
Ecotoxicology and environmental safety
Jul 14, 2025
BACKGROUND: Although the relationship between environmental pollutants and respiratory health has received widespread attention, no studies have explored the association between volatile organic compounds (VOCs) and preserved ratio impaired spirometr...
BACKGROUND: The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there have been minimal efforts to str...
BMC medical informatics and decision making
Jul 14, 2025
OBJECTIVES: Timely intervention in shock is vital, as delays over one hour greatly increase mortality. This study aims to develop an enhanced machine learning model that improves predictive performance by utilizing self-controlled data and applying f...
BACKGROUND: Missing survey data can threaten the validity and generalizability of findings from longitudinal cohort studies. Respondent characteristics and survey attributes may contribute to patterns of survey non-completion, a form of missing data ...
BACKGROUND: Accurately distinguishing the different molecular subtypes of 2021 World Health Organization (WHO) grade 4 Central Nervous System (CNS) gliomas is highly relevant for prognostic stratification and personalized treatment.
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