Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurodegenerative disease with a median survival of only 2 to 4 years from diagnosis. Improved tools are needed to shorten diagnostic delays and improve prognostication to benefit clinical care....
The Kashgar region, located in Northwest China, has a significantly higher incidence of tuberculosis (TB) compared to the national average. Local governments conduct annual TB screening using medical imaging. However, due to a shortage of radiologist...
Acute ischemic stroke is a major global health challenge, leading to long-term disability or death without timely intervention. Among neuroimaging modalities, spatio-temporal (4D) computed tomography perfusion (CTP) is widely used to assess cerebral ...
Humans are exposed to a multitude of environmental chemical mixtures (ECMs) in daily life that may influence depression risk. While prior studies have shown individual ECM exposures to depression, the cumulative and interactive effects of multiple co...
Depression, which is increasingly prevalent among older adults, has traditionally been diagnosed through symptom-based questionnaires. However, emerging evidence suggests that retinal changes could serve as objective biomarkers for depression. In thi...
While previous studies have reported functional abnormalities in the prefrontal-limbic-subcortical circuit, the treatment effects on this activity remain unclear. This longitudinal study aimed to investigate spontaneous brain activity in bipolar diso...
BACKGROUND: Coronary artery disease (CAD) is one of the biggest causes of mortality worldwide. Risk stratification for early detection is essential for the primary prevention of CAD. QRISK3 is known to overestimate future CAD risk in some populations...
PURPOSE: This study evaluated the dynamic changes in the tumor microenvironment (TME) in patients with non-small cell lung cancer (NSCLC) and acquired resistance to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) using an ar...
OBJECTIVE: To utilize machine learning techniques to screen contrast-enhanced ultrasound (CEUS) parameters and clinical characteristics, aiming to differentiate diabetic nephropathy (DN) from non-diabetic renal disease (NDRD) in patients with diabeti...
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