Purpose To develop and evaluate a deep learning-based prognostic model for predicting survival in locoregionally advanced nasopharyngeal carcinoma (LA-NPC) using serial MRI before and after induction chemotherapy (IC). Materials and Methods This mult...
Journal of cellular and molecular medicine
Jun 1, 2024
In patients with nasopharyngeal carcinoma (NPC), the alteration of immune responses in peripheral blood remains unclear. In this study, we established an immune cell profile for patients with NPC and used flow cytometry and machine learning (ML) to i...
Technology in cancer research & treatment
Jan 1, 2024
Intensity-modulated radiotherapy (IMRT) is currently the most important treatment method for nasopharyngeal carcinoma (NPC). This study aimed to enhance prediction accuracy by incorporating dose information into a deep convolutional neural network (...
Combinatorial chemistry & high throughput screening
Jan 1, 2023
IMPORTANCE: Accurate pre-treatment prediction of distant metastasis in patients with Nasopharyngeal Carcinoma (NPC) enables the implementation of appropriate treatment strategies for high-risk individuals.
BACKGROUND: Manual segment target volumes were time-consuming and inter-observer variability couldn't be avoided. With the development of computer science, auto-segmentation had the potential to solve this problem.
Journal of the National Cancer Institute
May 4, 2021
BACKGROUND: Images from magnetic resonance imaging (MRI) are crucial unstructured data for prognostic evaluation in nasopharyngeal carcinoma (NPC). We developed and validated a prognostic system based on the MRI features and clinical data of locoregi...
Technology in cancer research & treatment
Jan 1, 2021
To generate synthetic CT (sCT) images with high quality from CBCT and planning CT (pCT) for dose calculation by using deep learning methods. 169 NPC patients with a total of 20926 slices of CBCT and pCT images were included. In this study the Cycle...
PURPOSE: To identify optimal machine learning methods for radiomics-based differentiation of local recurrence versus inflammation from post-treatment nasopharyngeal positron emission tomography/X-ray computed tomography (PET/CT) images.