Nasopharyngeal carcinoma (NPC) is a malignancy with unique clinical biological profiles such as associated Epstein-Barr virus infection and high radiosensitivity. Radiotherapy has long been recognized as the mainstay for the treatment of NPC. However...
Survival analyses of populations and the establishment of prognoses for individual patients are important activities in the practice of medicine. Standard survival models, such as the Cox proportional hazards model, require extensive feature engineer...
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 11, 2019
PURPOSE: We aimed to evaluate the value of deep learning on positron emission tomography with computed tomography (PET/CT)-based radiomics for individual induction chemotherapy (IC) in advanced nasopharyngeal carcinoma (NPC).
Background Nasopharyngeal carcinoma (NPC) may be cured with radiation therapy. Tumor proximity to critical structures demands accuracy in tumor delineation to avoid toxicities from radiation therapy; however, tumor target contouring for head and neck...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 25, 2019
BACKGROUND: The purpose/aim of this study was to 1) use magnetic resonance diffusion tensor imaging (DTI), fibre bundle/tract-based spatial statistics (TBSS) and machine learning methods to study changes in the white matter (WM) structure and whole b...
Multi-modality examinations have been extensively applied in current clinical cancer management. Leveraging multi-modality medical images can be highly beneficial for automated tumor segmentation as they provide complementary information that could m...
OBJECTIVE: Accurate detection and segmentation of organs at risks (OARs) in CT image is the key step for efficient planning of radiation therapy for nasopharyngeal carcinoma (NPC) treatment. We develop a fully automated deep-learning-based method (te...
BACKGROUND: According to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system, over 50% of patients with nasopharyngeal carcinoma (NPC) have N1 disease at initial diagnosis. However, patients with N1 NPC are relatively unde...
We aimed to identify optimal machine-learning methods for radiomics-based prediction of local failure and distant failure in advanced nasopharyngeal carcinoma (NPC). We enrolled 110 patients with advanced NPC. A total of 970 radiomic features were ex...
Neural networks : the official journal of the International Neural Network Society
Sep 1, 2025
Nasopharyngeal carcinoma (NPC) is a malignant tumor that originates from the back of the nasal canal from above the soft palate to the upper larynx. Because the nasopharyngeal location is deeply hidden, it is often difficult for a single imaging mean...
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