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Neoplasm Grading

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Clinical-grade computational pathology using weakly supervised deep learning on whole slide images.

Nature medicine
The development of decision support systems for pathology and their deployment in clinical practice have been hindered by the need for large manually annotated datasets. To overcome this problem, we present a multiple instance learning-based deep lea...

Image-Guided Robotic Radiosurgery for Treatment of Recurrent Grade II and III Meningiomas. A Single-Center Study.

World neurosurgery
OBJECTIVE: Stereotactic radiosurgery (SRS) has been increasingly applied for malignant meningiomas as an alternative to conventionally fractioned radiation therapy. We performed a retrospective analysis of an institutional patient cohort with maligna...

In-Bore Transrectal MRI-Guided Biopsy With Robotic Assistance in the Diagnosis of Prostate Cancer: An Analysis of 57 Patients.

AJR. American journal of roentgenology
The objective of our study was to analyze the feasibility and potential role of robotic-assisted transrectal MRI-guided biopsy for the diagnosis of prostate cancer. A total of 57 patients (mean age, 67 ± 6 [SD] years; age range, 57-83 years; mean p...

Combination possibility and deep learning model as clinical decision-aided approach for prostate cancer.

Health informatics journal
This study aims to introduce as proof of concept a combination model for classification of prostate cancer using deep learning approaches. We utilized patients with prostate cancer who underwent surgical treatment representing the various conditions ...

Machine learning classifiers can predict Gleason pattern 4 prostate cancer with greater accuracy than experienced radiologists.

European radiology
OBJECTIVE: The purpose of this study was: To test whether machine learning classifiers for transition zone (TZ) and peripheral zone (PZ) can correctly classify prostate tumors into those with/without a Gleason 4 component, and to compare the performa...

Breast cancer outcome prediction with tumour tissue images and machine learning.

Breast cancer research and treatment
PURPOSE: Recent advances in machine learning have enabled better understanding of large and complex visual data. Here, we aim to investigate patient outcome prediction with a machine learning method using only an image of tumour sample as an input.

Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies.

Virchows Archiv : an international journal of pathology
Histopathologic grading of prostate cancer using Gleason patterns (GPs) is subject to a large inter-observer variability, which may result in suboptimal treatment of patients. With the introduction of digitization and whole-slide images of prostate b...

A quantitative SVM approach potentially improves the accuracy of magnetic resonance spectroscopy in the preoperative evaluation of the grades of diffuse gliomas.

NeuroImage. Clinical
OBJECTIVES: To investigate the association between proton magnetic resonance spectroscopy (H-MRS) metabolic features and the grade of gliomas, and to establish a machine-learning model to predict the glioma grade.

Application of Artificial Intelligence for Preoperative Diagnostic and Prognostic Prediction in Epithelial Ovarian Cancer Based on Blood Biomarkers.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: We aimed to develop an ovarian cancer-specific predictive framework for clinical stage, histotype, residual tumor burden, and prognosis using machine learning methods based on multiple biomarkers.