Clinical cancer research : an official journal of the American Association for Cancer Research
Jan 16, 2026
PURPOSE: Despite current standard-of-care endocrine therapy, distant recurrence remains a concern for patients with hormone receptor-positive (HR+)/HER2- early breast cancer (EBC). Understanding individual recurrence risk would aid in clinical decisi...
BACKGROUND: Gastric cancer (GC) is a highly heterogeneous disease, and the response of patients to clinical treatment varies substantially. There is no satisfactory strategy for predicting curative effects to date. We aimed to explore a new method fo...
Clinical cancer research : an official journal of the American Association for Cancer Research
Nov 14, 2025
PURPOSE: Treatment with immune checkpoint inhibitors (ICI) in advanced melanoma can result in durable responses, yet an algorithm to decide which patients can safely discontinue ICI is still lacking.
BACKGROUND: For solitary papillary thyroid carcinoma on the isthmic (SPTCI), there are currently no specific guidelines for the extent of resection and lymph node dissection. This study aims to explore the surgical strategies suitable for patients wi...
INTRODUCTION: We assessed the outcomes of stereotactic radiosurgery (SRS) for small intact brain metastases (SBM) (≤ 2 cm) and developed machine learning (ML) algorithms to predict the probability of local failure (LF).
Computer methods and programs in biomedicine
Sep 1, 2025
BACKGROUND AND OBJECTIVE: Colorectal cancer (CRC) ranks among the most prevalent cancers worldwide, with early postoperative recurrence remaining a major cause of mortality. Body composition and inflammatory-nutritional indices (BCINI) have demonstra...
PURPOSE OF REVIEW: Biochemical recurrence (BCR) after radical prostatectomy exhibits heterogeneous prognostic implications. Recent advancements in imaging and biomarkers have high potential for personalizing care.
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, with high rates of post-resection recurrence posing significant clinical challenges. Early recurrence is largely driven by aggressive tumor biology, while late recurr...
Journal of cellular and molecular medicine
Aug 1, 2025
Liver resection remains the mainstay curative treatment for hepatocellular carcinoma (HCC); however, the recurrence rate is reported to exceed 70% within 5 years after surgery. Microvascular invasion (MVI) has attracted great research interest in the...
Clinical nutrition (Edinburgh, Scotland)
Aug 1, 2025
BACKGROUND: Artificial intelligence enables automated three-dimensional (3D) volumetric body composition (BC) analysis from computed tomography (CT), opposed to single third lumbar vertebra (L3) slices alone. This study aimed to identify relationship...
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