Bovine papillomavirus (BPV) is considered a useful model to study HPV oncogenic process. BPV interacts with the host chromatin, resulting in DNA damage, which is attributed to E5, E6, and E7 viral oncoproteins activity. However, the oncogenic mechani...
Cancer prevention research (Philadelphia, Pa.)
Sep 2, 2025
UNLABELLED: Cervical cancer is one of the most common cancers in women. Despite progress in prevention and success in early detection through cytologic screening and human papillomavirus (HPV) detection, there remains a challenge in triaging women ap...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The early detection of high-risk human papillomavirus (HR-HPV) is crucial for the assessment and improvement of prognosis in cervical cancer. However, existing PCR-based screening methods suffer from inadequate accessibility, which dampens the enthus...
Zhonghua zhong liu za zhi [Chinese journal of oncology]
Feb 23, 2025
Using methylation characteristics of human genes to construct machine learning predictive models for screening cervical cancer and precancerous lesions. Human DNA methylation detection was performed on 224 cervical exfoliated cell specimens from th...
HPV status is an important prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC), with HPV-positive tumors associated with better overall survival. To determine HPV status, we rely on the immunohistochemical investigation for expression ...
Human papillomavirus (HPV) integrating into human genome is the main cause of cervical carcinogenesis. HPV integration selection preference shows strong dependence on local genomic environment. Due to this theory, it is possible to predict HPV integr...
From initial human papillomavirus (HPV) infection and precursor stages, the development of cervical cancer takes decades. High-sensitivity HPV DNA testing is currently recommended as primary screening method for cervical cancer, whereas better triage...
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
Mar 1, 2019
The objective of this study was to determine whether the pretreatment human papillomavirus (HPV) genotype might predict the risk of cervical dysplasia persistence/recurrence. Retrospective analysis of prospectively collected data of consecutive 5104 ...
Studies in health technology and informatics
Jan 1, 2017
HPV vaccination refusal is a serious public health issue. Opinions on Twitter have are influential to potential consumers on vaccination behaviours. Public opinions toward HPV vaccination were extracted from Twitter by leveraging machine learning mod...
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