AIMC Topic: Positron-Emission Tomography

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Empowering PET imaging reporting with retrieval-augmented large language models and reading reports database: a pilot single center study.

European journal of nuclear medicine and molecular imaging
PURPOSE: The potential of Large Language Models (LLMs) in enhancing a variety of natural language tasks in clinical fields includes medical imaging reporting. This pilot study examines the efficacy of a retrieval-augmented generation (RAG) LLM system...

Modernizing Neuro-Oncology: The Impact of Imaging, Liquid Biopsies, and AI on Diagnosis and Treatment.

International journal of molecular sciences
Advances in neuro-oncology have transformed the diagnosis and management of brain tumors, which are among the most challenging malignancies due to their high mortality rates and complex neurological effects. Despite advancements in surgery and chemor...

Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospective observational study.

Alzheimer's research & therapy
BACKGROUND: Intracerebral amyloid β (Aβ) accumulation is considered the initial observable event in the pathological process of Alzheimer's disease (AD). Efficient screening for amyloid pathology is critical for identifying patients for early treatme...

Clinical impact of an explainable machine learning with amino acid PET imaging: application to the diagnosis of aggressive glioma.

European journal of nuclear medicine and molecular imaging
PURPOSE: Radiomics-based machine learning (ML) models of amino acid positron emission tomography (PET) images have shown efficiency in glioma prediction tasks. However, their clinical impact on physician interpretation remains limited. This study inv...

Clinical validation of artificial intelligence-based single-subject morphometry without normative reference database.

Journal of Alzheimer's disease : JAD
BACKGROUND: Single-subject voxel-based morphometry (VBM) is a powerful technique for reader-independent detection of brain atrophy in structural magnetic resonance imaging (MRI) to support the (differential) diagnosis and staging of neurodegenerative...

Explainable PET-Based Habitat and Peritumoral Machine Learning Model for Predicting Progression-free Survival in Clinical Stage IA Pure-Solid Non-small Cell Lung Cancer: A Two-center Study.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop and validate machine learning (ML) models utilizing positron emission tomography (PET)-habitat of the tumor and its peritumoral microenvironment to predict progression-free survival (PFS) in patie...

The Value of Machine Learning-based Radiomics Model Characterized by PET Imaging with Ga-FAPI in Assessing Microvascular Invasion of Hepatocellular Carcinoma.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop a radiomics model characterized by Ga-fibroblast activation protein inhibitors (FAPI) positron emission tomography (PET) imaging to predict microvascular invasion (MVI) of hepatocellular carcinoma...

A multi-view learning approach with diffusion model to synthesize FDG PET from MRI T1WI for diagnosis of Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: This study presents a novel multi-view learning approach for machine learning (ML)-based Alzheimer's disease (AD) diagnosis.

Self-supervised neural network for Patlak-based parametric imaging in dynamic [F]FDG total-body PET.

European journal of nuclear medicine and molecular imaging
PURPOSE: The objective of this study is to generate reliable K parametric images from a shortened [F]FDG total-body PET for clinical applications using a self-supervised neural network algorithm.

3D full-dose brain-PET volume recovery from low-dose data through deep learning: quantitative assessment and clinical evaluation.

European radiology
OBJECTIVES: Low-dose (LD) PET imaging would lead to reduced image quality and diagnostic efficacy. We propose a deep learning (DL) method to reduce radiotracer dosage for PET studies while maintaining diagnostic quality.