Isocitrate dehydrogenase-mutant gliomas are lethal brain cancers that impair quality of life in young adults. Although less aggressive than glioblastomas, IDH-mutant gliomas invariably progress to incurable disease with unpredictable recurrence. A be...
Alzheimer's disease (AD) represents a significant challenge due to its progressive neurodegenerative impact, particularly within an aging global demographic. This underscores the critical need for developing sophisticated diagnostic tools for its ear...
Amyloid- positron emission tomography can reflect the Amyloid- protein deposition in the brain and thus serves as one of the golden standards for Alzheimer's disease (AD) diagnosis. However, its practical cost and high radioactivity hinder its applic...
Low-dose PET offers a valuable means of minimizing radiation exposure in PET imaging. However, the prevalent practice of employing additional CT scans for generating attenuation maps ( -map) for PET attenuation correction significantly elevates radia...
Psychiatry and clinical neurosciences
Mar 31, 2025
AIMS: Effective intervention for mild cognitive impairment (MCI) is key for preventing dementia. As a neuroprotective agent, butylphthalide has the potential to treat MCI due to Alzheimer disease (AD). However, the pharmacological mechanism of butylp...
OBJECTIVE: This study aimed to develop and validate a nomogram combining F-FDG PET radiomics and clinical factors to non-invasively predict bone marrow involvement (BMI) in patients with lymphoma.
The advent of sophisticated image analysis techniques has facilitated the extraction of increasingly complex data, such as radiomic features, from various imaging modalities, including [F]FDG PET/CT, a well-established cornerstone of oncological imag...
Journal of cancer research and clinical oncology
Mar 28, 2025
PURPOSE: To explore the development and validation of automated machine learning (AutoML) models for F-FDG PET imaging-based radiomics signatures to predict treatment response in elderly patients with diffuse large B-cell lymphoma (DLBCL).
Critical reviews in oncology/hematology
Mar 24, 2025
The choice of imaging modalities is essential in sarcoma management, as different techniques provide complementary information depending on tumor subtype and anatomical location. This narrative review examines the role of imaging in sarcoma character...
Nanomaterials represent an innovation in cancer imaging by offering enhanced contrast, improved targeting capabilities, and multifunctional imaging modalities. Recent advancements in material engineering have enabled the development of nanoparticles ...
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