Prostate adenocarcinoma (PAC) is a complex and common cancer in males and is one of the leading causes of cancer-related death globally. PAC is a multifaceted disease that encompasses different subtypes, including acinar and ductal adenocarcinoma, sm...
International journal of molecular sciences
Mar 12, 2025
Chronic myeloid leukemia is a clonal hematologic disease characterized by the presence of the Philadelphia chromosome and the BCR::ABL1 fusion protein. Integrating different molecular, genetic, clinical, and laboratory data would improve the diagnost...
Frontiers in cellular and infection microbiology
Mar 11, 2025
BACKGROUND: Although highly active antiretroviral therapy (HAART) has greatly enhanced the prognosis for people living with HIV (PLWH), some individuals fail to achieve adequate immune reconstitution, known as immunological nonresponse (INR), which i...
BACKGROUND: The presence of tumour-infiltrating lymphocytes (TILs) is a well-established prognostic biomarker across multiple cancer types, with higher TIL counts being associated with lower recurrence rates and improved patient survival. We aimed to...
BACKGROUND: Currently, there is a lack of effective early assessment tools for predicting the onset and development of cardiac arrest (CA). With the increasing attention of clinical researchers on machine learning (ML), some researchers have develope...
International journal of medical informatics
Mar 8, 2025
BACKGROUND: Diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) induces psychological variables and treatment-related toxicity in patients. The evaluation of outcomes is warranted for effective treatment planning and improved dis...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Mar 7, 2025
Understanding the prognosis of cancer patients is crucial for enabling precise diagnosis and treatment by clinical practitioners. Multimodal fusion models based on artificial intelligence (AI) offer a comprehensive depiction of the tumor heterogeneit...
BACKGROUND: Thyroid cancer is a prevalent malignancy requiring accurate subtype identification for effective treatment planning and prognosis evaluation. Deep learning has emerged as a valuable tool for analyzing tumor microenvironment features and d...
Hepatocellular carcinoma (HCC) is an exceedingly aggressive form of cancer that often carries a poor prognosis, especially when it is complicated by the presence of microvascular invasion (MVI). Identifying patients at high risk of MVI is crucial for...
No studies have examined the prognostic value of the log odds of negative lymph nodes/T stage (LONT) in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT). We aimed to assess the prognostic value of LONT and devel...