AIMC Topic: Prognosis

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Foam sclerotherapy for symptomatic cysts in ADPKD, ADPLD and solitary cysts.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
BACKGROUND: This medical center migrated from alcohol to sotradecol foam sclerotherapy (SFS) because of perceived improved efficacy in managing symptomatic kidney and liver cysts. We report technical aspects, change in short- and long-term cyst volum...

Prognostication in patients with idiopathic pulmonary fibrosis using quantitative airway analysis from HRCT: a retrospective study.

The European respiratory journal
BACKGROUND: Predicting shorter life expectancy is crucial for prioritising antifibrotic therapy in fibrotic lung diseases (FLDs), where progression varies widely, from stability to rapid deterioration. This heterogeneity complicates treatment decisio...

Machine learning and explainable artificial intelligence reveals the MicroRNAs associated with survival of head and neck squamous cell carcinoma patients.

Computational biology and chemistry
Dysregulated microRNAs (miRNAs) play a significant role in cancer development and metastasis. In literature, miRNAs have been used for the survival prediction of different types of cancers using AI. Although AI is useful for diagnosis and prognosis p...

Machine learning-driven programmed cell death signature for prognosis and drug candidate discovery in diffuse large B-cell lymphoma: Multi-cohort study and experimental validation.

International immunopharmacology
BACKGROUND: Relapse and drug resistance are major contributor to chemotherapy failure in diffuse large B-cell lymphoma (DLBCL). Programmed cell death (PCD), a key mechanism in tumor progression and resistance, has emerged as a promising biomarker for...

[Research on risk prediction of acute respiratory distress syndrome complicated with acute kidney injury: progress and challenges].

Zhonghua yi xue za zhi
The risk of acute respiratory distress syndrome (ARDS) combined with acute kidney injury (AKI) is high and the prognosis is poor. Therefore, there is an urgent need for efficient and accurate methods to improve clinical doctors' early diagnosis and p...

Associations between Calcium Intake and T-cell Infiltration in Colorectal Tumors.

Cancer prevention research (Philadelphia, Pa.)
UNLABELLED: Higher T-cell infiltration in colorectal tumors has been associated with better prognosis. Evidence indicates that calcium signaling is essential for T-cell functioning. However, as it is unknown whether calcium intake influences T-cell i...

Alternations of Gut Microbiome and Serum Metabolome With Prolongation of the Course of Type 1 Diabetes Mellitus.

Diabetes/metabolism research and reviews
AIMS: We aimed to explore the gut microbial and serum metabolic disturbances associated with the course of type 1 diabetes mellitus (T1DM), and identify potential biomarkers for discriminating T1DM from normoglycemia individuals by machine learning.

Moving past multidisciplinary discussions and Gender-Age-Physiology model: precision medicine through biological phenotyping in interstitial lung disease.

Current opinion in pulmonary medicine
PURPOSE OF REVIEW: Interstitial lung disease (ILD) presents significant diagnostic and therapeutic challenges due to underlying biological heterogeneity and variable clinical course. Traditional diagnostic and prognostic tools are limited in their ab...

Leveraging machine learning and single-cell RNA sequencing strategies to develop a risk prognosis scoring based on liquid-liquid phase separation feature genes in pediatric hepatoblastoma.

Computers in biology and medicine
BACKGROUND: Considerable evidence highlights the intricate association between liquid-liquid phase separation (LLPS) and tumorigenesis, progression, and therapy resistance. However, there has been limited exploration of the role of LLPS in hepatoblas...

Gaucher disease, state of the art and perspectives.

Journal of internal medicine
Knowledge about Gaucher disease (GD), considered a model for rare diseases, has considerably increased since its discovery. The pathophysiology of this lysosomal disorder is better known, and specific therapies that can control many aspects of the di...