Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny
May 10, 2025
The chronic cardiac deficiency continues to be one of the leading health care problems requiring innovative solutions. The article presents mathematical algorithm to evaluate drug interactions and targeted to minimize side effects and to optimize chr...
BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer and a leading cause of cancer-related deaths globally. The tumour microenvironment (TME) influences treatment response and prognosis, yet its heterogeneity remains ...
Patients with intracerebral hemorrhage (ICH) are highly susceptible to sepsis. This study evaluates the efficacy of machine learning (ML) models in predicting sepsis risk in intensive care units (ICUs) patients with ICH. We conducted a retrospective ...
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
May 9, 2025
Accurate breast cancer prognosis helps clinicians in selecting optimal treatments, potentially improving patient survival. We tested whether combining deep learning with tumor histopathology images could reliably predict cancer spread. Advantages of ...
International journal of molecular sciences
May 9, 2025
Long non-coding RNAs (lncRNAs) could alter the tumor immune microenvironment and regulate the expression of immune checkpoints (ICPs) by regulating target genes in tumors. However, only a few lncRNAs have precise functions in immunity and potential f...
BACKGROUND: Stress hyperglycemia ratio (SHR) and glycemic variability (GV) reflect acute glucose elevation and fluctuations, which correlate with adverse outcomes in patients with atherosclerotic cardiovascular disease (ASCVD). However, the prognosti...
This study aims to predict hemorrhagic stroke outcomes, including 90-day prognosis and in-hospital mortality, using machine learning models and SHapley Additive exPlanations (SHAP) analysis. Data were collected from a national Stroke Registry from Ja...
While neoadjuvant chemotherapy combined with surgical resection has improved the prognosis for patients with osteosarcoma, its impact on metastatic and recurrent cases remains limited. Immunotherapy is emerging as a promising alternative. However, th...
Cancer immunology, immunotherapy : CII
May 9, 2025
PURPOSE: The aim of this study is to better characterize the clinical characteristics and outcomes of patients diagnosed with Immune checkpoint Inhibitor (ICI) pneumonitis and propose predictive models.
Breast cancer liver metastasis (BCLM) presents a critical challenge in breast cancer treatment and has substantial epidemiological and clinical significance. Receptor status is pivotal in managing both primary breast cancer and its liver metastases. ...
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