Accurate cancer prognosis is essential for personalized clinical management, guiding treatment strategies and predicting patient survival. Conventional methods, which depend on the subjective evaluation of histopathological features, exhibit signific...
High-throughput sequencing technologies have facilitated a deeper exploration of prognostic biomarkers. While many deep learning (DL) methods primarily focus on feature extraction or employ simplistic fully connected layers within prognostic modules,...
European heart journal. Cardiovascular Imaging
Mar 3, 2025
AIMS: Identification of proximal coronary artery calcium (CAC) may improve prediction of major adverse cardiac events (MACE) beyond the CAC score, particularly in patients with low CAC burden. We investigated whether the proximal CAC can be detected ...
Journal of cellular and molecular medicine
Mar 1, 2025
Using machine learning approaches, we developed and validated a novel prognostic model for oesophageal squamous cell carcinoma (ESCC) based on glycolipid metabolism-related genes. Through integrated analysis of TCGA and GEO datasets, we established a...
INTRODUCTION: Nasopharyngeal carcinoma (NPC) typically presents as advanced disease due to the lack of significant symptoms in the early stages. Accurate prognostication is therefore challenging as current methods based on anatomical staging often la...
Purpose To develop deep learning (DL) radiopathomics models based on contrast-enhanced MRI and pathologic imaging to predict vessels encapsulating tumor clusters (VETC) and survival in hepatocellular carcinoma (HCC). Materials and Methods In this ret...
BACKGROUND: Gastric cancer (GC) is considered a highly heterogeneous disease, and currently, a comprehensive approach encompassing molecular data from various biological levels is lacking.
Journal of the American College of Radiology : JACR
Mar 1, 2025
BACKGROUND: Prekidney transplant evaluation routinely includes abdominal CT for presurgical vascular assessment. A wealth of body composition data are available from these CT examinations, but they remain an underused source of data, often missing fr...
BACKGROUND: There are significant disparities in outcomes at the end-of-life (EOL) for minoritized patients with advanced cancer, with most dying without a documented serious illness conversation (SIC). This study aims to assess clinician perceptions...
Liver international : official journal of the International Association for the Study of the Liver
Mar 1, 2025
BACKGROUND & AIMS: Microvascular invasion (MVI) is associated with poor prognosis in hepatocellular carcinoma (HCC). Topology may improve the predictive performance and interpretability of deep learning (DL). We aimed to develop and externally valida...
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