AIMC Topic: Prostatic Neoplasms

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Objective risk stratification of prostate cancer using machine learning and radiomics applied to multiparametric magnetic resonance images.

Scientific reports
Multiparametric magnetic resonance imaging (mpMRI) has become increasingly important for the clinical assessment of prostate cancer (PCa), but its interpretation is generally variable due to its relatively subjective nature. Radiomics and classificat...

Dose evaluation of MRI-based synthetic CT generated using a machine learning method for prostate cancer radiotherapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Magnetic resonance imaging (MRI)-only radiotherapy treatment planning is attractive since MRI provides superior soft tissue contrast over computed tomographies (CTs), without the ionizing radiation exposure. However, it requires the generation of a s...

A feasibility study for predicting optimal radiation therapy dose distributions of prostate cancer patients from patient anatomy using deep learning.

Scientific reports
With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would alleviate thi...

Prostate cancer classification with multiparametric MRI transfer learning model.

Medical physics
PURPOSE: Prostate cancer classification has a significant impact on the prognosis and treatment planning of patients. Currently, this classification is based on the Gleason score analysis of biopsied tissues, which is neither accurate nor risk free. ...

Detection of Extraprostatic Extension of Cancer on Biparametric MRI Combining Texture Analysis and Machine Learning: Preliminary Results.

Academic radiology
RATIONALE AND OBJECTIVES: Extraprostatic extension of disease (EPE) has a major role in risk stratification of prostate cancer patients. Currently, pretreatment local staging is performed with MRI, while the gold standard is represented by histopatho...

Optimization based trajectory planning for real-time 6DoF robotic patient motion compensation systems.

PloS one
PURPOSE: Robotic stabilization of a therapeutic radiation beam with respect to a dynamically moving tumor target can be accomplished either by moving the radiation source, the patient, or both. As the treatment beam is on during this process, the pri...

Machine learning-based radiomic models to predict intensity-modulated radiation therapy response, Gleason score and stage in prostate cancer.

La Radiologia medica
OBJECTIVE: To develop different radiomic models based on the magnetic resonance imaging (MRI) radiomic features and machine learning methods to predict early intensity-modulated radiation therapy (IMRT) response, Gleason scores (GS) and prostate canc...

Focusing aptamer selection on the glycan structure of prostate-specific antigen: Toward more specific detection of prostate cancer.

Biosensors & bioelectronics
The development of chemical sensors capable of detecting the specific glycosylation patterns of proteins offers a powerful mean for the early detection of cancer. Unfortunately, this strategy is scarcely explored because receptors recognizing the gly...

Identifying Cases of Metastatic Prostate Cancer Using Machine Learning on Electronic Health Records.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Cancer stage is rarely captured in structured form in the electronic health record (EHR). We evaluate the performance of a classifier, trained on structured EHR data, in identifying prostate cancer patients with metastatic disease. Using EHR data for...