AIMC Topic: Proteolysis

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DiffPROTACs is a deep learning-based generator for proteolysis targeting chimeras.

Briefings in bioinformatics
PROteolysis TArgeting Chimeras (PROTACs) has recently emerged as a promising technology. However, the design of rational PROTACs, especially the linker component, remains challenging due to the absence of structure-activity relationships and experime...