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Radiopharmaceuticals

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Predicting standardized uptake value of brown adipose tissue from CT scans using convolutional neural networks.

Nature communications
The standard method for identifying active Brown Adipose Tissue (BAT) is [F]-Fluorodeoxyglucose ([F]-FDG) PET/CT imaging, which is costly and exposes patients to radiation, making it impractical for population studies. These issues can be addressed w...

Comparative evaluation of machine learning models in predicting overall survival for nasopharyngeal carcinoma using F-FDG PET-CT parameters.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
PURPOSE: The objective of this study is to assess the prognostic efficacy of F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET-CT) parameters in nasopharyngeal carcinoma (NPC) and identify the best machine learning (M...

Applying deep learning-based ensemble model to [F]-FDG-PET-radiomic features for differentiating benign from malignant parotid gland diseases.

Japanese journal of radiology
OBJECTIVES: To develop and identify machine learning (ML) models using pretreatment 2-deoxy-2-[F]fluoro-D-glucose ([F]-FDG)-positron emission tomography (PET)-based radiomic features to differentiate benign from malignant parotid gland diseases (PGDs...

The Potential of Gemini and GPTs for Structured Report Generation based on Free-Text F-FDG PET/CT Breast Cancer Reports.

Academic radiology
RATIONALE AND OBJECTIVE: To compare the performance of large language model (LLM) based Gemini and Generative Pre-trained Transformers (GPTs) in data mining and generating structured reports based on free-text PET/CT reports for breast cancer after u...

MIRD Pamphlet No. 31: MIRDcell V4-Artificial Intelligence Tools to Formulate Optimized Radiopharmaceutical Cocktails for Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Radiopharmaceutical cocktails have been developed over the years to treat cancer. Cocktails of agents are attractive because 1 radiopharmaceutical is unlikely to have the desired therapeutic effect because of nonuniform uptake by the targeted cells. ...

Automated deep learning segmentation of cardiac inflammatory FDG PET.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: Fluorodeoxyglucose positron emission tomography (FDG PET) with suppression of myocardial glucose utilization plays a pivotal role in diagnosing cardiac sarcoidosis. Reorientation of images to match perfusion datasets and myocardial segmen...

Clinical Pilot of a Deep Learning Elastic Registration Algorithm to Improve Misregistration Artifact and Image Quality on Routine Oncologic PET/CT.

Academic radiology
RATIONALE AND OBJECTIVES: Misregistration artifacts between the PET and attenuation correction CT (CTAC) exams can degrade image quality and cause diagnostic errors. Deep learning (DL)-warped elastic registration methods have been proposed to improve...

A support vector machine-based approach to guide the selection of a pseudo-reference region for brain PET quantification.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
A Support Vector Machine (SVM) based approach was developed to identify a pseudo-reference region for brain PET scans with the aim of reducing interscan and intersubject variability. By training a binary linear SVM classifier with PET datasets from t...