AIMC Topic: Retrospective Studies

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TET2 gene mutation status associated with poor prognosis of transition zone prostate cancer: a retrospective cohort study based on whole exome sequencing and machine learning models.

Frontiers in endocrinology
BACKGROUND: Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants and therapeutic vulnerabilities remain poorly characterized.

A retrospective study using machine learning to develop predictive model to identify rotavirus-associated acute gastroenteritis in children.

PeerJ
BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in children under 5 years worldwide. Timely diagnosis is critical, but access to confirmatory testing is limited in hospital settings. Machine learning (ML) models have shown p...

Development of a machine learning-based diagnostic model using hematological parameters to differentiate periductal mastitis from granulomatous lobular mastitis.

Science progress
ObjectiveNonpuerperal mastitis (NPM) is an inflammatory condition, including periductal mastitis (PDM) and granulomatous lobular mastitis (GLM). The clinical manifestations of PDM and GLM are highly similar, posing significant challenges in their dif...

Machine learning-based MRI radiomics to predict postoperative complications following peripheral nerve sheath tumour excision.

The Journal of hand surgery, European volume
This study sought to establish and validate a machine learning-based multi-sequence MRI radiomics model for predicting postoperative complications in patients with peripheral nerve sheath tumours. We conducted a retrospective analysis of 303 patients...

MRI radiomics combined with delta-radiomics model for predicting pathological complete response in locally advanced rectal cancer patients after neoadjuvant chemoradiotherapy: A multi-institutional study.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
PURPOSE: To construct and validate a magnetic resonance imaging (MRI) radiomics combined with delta-radiomics and clinical information (C) model for predicting pathological complete response (pCR) in patients with locally advanced rectal cancer (LARC...

Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing.

BMC infectious diseases
BACKGROUND: Remdesivir (RDV) was the first antiviral approved for mild-to-moderate COVID-19 and for those patients at risk for progression to severe disease after clinical trials supported its association with improved outcomes. Real-world evidence (...

A High-resolution T2WI-based Deep Learning Model for Preoperative Discrimination Between T2 and T3 Rectal Cancer: A Multicenter Study.

Academic radiology
RATIONALE AND OBJECTIVES: To construct a deep learning model (DL) based on high-resolution T2-weighted images for preoperative differentiation between T2 and T3 stage rectal cancer (RC), and to compare its performance with experienced radiologists.

Deep learning-based prediction of enhanced CT scans for lymph node metastasis in esophageal squamous cell carcinoma.

Japanese journal of radiology
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) poses a significant global health challenge with a particularly grim prognosis. Accurate prediction of lymph node metastasis (LNM) in ESCC is crucial for optimizing treatment strategies and improv...