AIMC Topic: RNA, Ribosomal, 16S

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Insight into endophytic microbiota-driven geographical and bioactive signatures toward a novel quality assessment model for Codonopsis Radix.

Plant physiology and biochemistry : PPB
Codonopsis Radix, a medicinal and dietary herb in traditional Chinese medicine, largely owes its pharmacological efficacy to both intrinsic phytochemistry and symbiotic interactions with plant-associated microbes. Here, we deciphered the geo-environm...

The Influence of an AI-Driven Personalized Nutrition Program on the Human Gut Microbiome and Its Health Implications.

Nutrients
Personalized nutrition programs enhanced with artificial intelligence (AI)-based tools hold promising potential for the development of healthy and sustainable diets and for disease prevention. This study aimed to explore the impact of an AI-based pe...

Exploring non-invasive biomarkers for pulmonary nodule detection based on salivary microbiomics and machine learning algorithms.

Scientific reports
Microorganisms are one of the most promising biomarkers for cancer, and the relationship between microorganisms and lung cancer occurrence and development provides significant potential for pulmonary nodule (PN) diagnosis from a microbiological persp...

Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures.

Journal of translational medicine
BACKGROUND: Prior studies have elucidated that alterations in gut microbiota are associated with a spectrum of tumors and metabolic disorders. However, the diagnostic value of gut microbiota in epithelial ovarian cancer remains insufficiently investi...

Machine-learning assisted discovery unveils novel interplay between gut microbiota and host metabolic disturbance in diabetic kidney disease.

Gut microbes
Diabetic kidney disease (DKD) is a serious healthcare dilemma. Nonetheless, the interplay between the functional capacity of gut microbiota and their host remains elusive for DKD. This study aims to elucidate the functional capability of gut microbio...

Cloning, Characterization, and Computer-Aided Evolution of a Thermostable Laccase of the DUF152 Family From Klebsiella michiganensis.

Proteins
Bacterial laccases exhibit relatively high optimal reaction temperatures and possess a broad substrate spectrum, thereby expanding the range of potential applications for laccase enzymes. This study aims to investigate the molecular evolution of bact...

Optimizing the production and efficacy of antimicrobial bioactive compounds from in combating multi-drug-resistant pathogens.

Frontiers in cellular and infection microbiology
BACKGROUND: The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of ...

Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution.

Frontiers in cellular and infection microbiology
BACKGROUND: Yin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body...

Identifying human activities causing water pollution based on microbial community sequencing and source classifier machine learning.

Environment international
Identifying and differentiating human activities is crucial for effectively preventing the threats posed by environmental pollution to aquatic ecosystems and human health. Machine learning (ML) is a powerful analytical tool for tracking human impacts...

Comparative analysis of the human microbiome from four different regions of China and machine learning-based geographical inference.

mSphere
The human microbiome, the community of microorganisms that reside on and inside the human body, is critically important for health and disease. However, it is influenced by various factors and may vary among individuals residing in distinct geographi...