AIMC Topic: Sensitivity and Specificity

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Correlation-Based Ensemble Feature Selection Using Bioinspired Algorithms and Classification Using Backpropagation Neural Network.

Computational and mathematical methods in medicine
A framework for clinical diagnosis which uses bioinspired algorithms for feature selection and gradient descendant backpropagation neural network for classification has been designed and implemented. The clinical data are subjected to data preprocess...

Automated Echocardiographic Quantification of Left Ventricular Ejection Fraction Without Volume Measurements Using a Machine Learning Algorithm Mimicking a Human Expert.

Circulation. Cardiovascular imaging
BACKGROUND: Echocardiographic quantification of left ventricular (LV) ejection fraction (EF) relies on either manual or automated identification of endocardial boundaries followed by model-based calculation of end-systolic and end-diastolic LV volume...

A superpixel-driven deep learning approach for the analysis of dermatological wounds.

Computer methods and programs in biomedicine
BACKGROUND: The image-based identification of distinct tissues within dermatological wounds enhances patients' care since it requires no intrusive evaluations. This manuscript presents an approach, we named QTDU, that combines deep learning models wi...

LDAPred: A Method Based on Information Flow Propagation and a Convolutional Neural Network for the Prediction of Disease-Associated lncRNAs.

International journal of molecular sciences
Long non-coding RNAs (lncRNAs) play a crucial role in the pathogenesis and development of complex diseases. Predicting potential lncRNA-disease associations can improve our understanding of the molecular mechanisms of human diseases and help identify...

Automatic detection of epileptic seizure based on approximate entropy, recurrence quantification analysis and convolutional neural networks.

Artificial intelligence in medicine
Epilepsy is the most common neurological disorder in humans. Electroencephalogram is a prevalent tool for diagnosing the epileptic seizure activity in clinical, which provides valuable information for understanding the physiological mechanisms behind...

Utilizing supervised machine learning to identify microglia and astrocytes in situ: implications for large-scale image analysis and quantification.

Journal of neuroscience methods
BACKGROUND: The evaluation of histological tissue samples plays a crucial role in deciphering preclinical disease and injury mechanisms. High-resolution images can be obtained quickly however data acquisition are often bottlenecked by manual analysis...

Prevalence and Predictability of Low-Yield Inpatient Laboratory Diagnostic Tests.

JAMA network open
IMPORTANCE: Laboratory testing is an important target for high-value care initiatives, constituting the highest volume of medical procedures. Prior studies have found that up to half of all inpatient laboratory tests may be medically unnecessary, but...

Predicting lung nodule malignancies by combining deep convolutional neural network and handcrafted features.

Physics in medicine and biology
To predict lung nodule malignancy with a high sensitivity and specificity for low dose CT (LDCT) lung cancer screening, we propose a fusion algorithm that combines handcrafted features (HF) into the features learned at the output layer of a 3D deep c...

Semi-automatic classification of prostate cancer on multi-parametric MR imaging using a multi-channel 3D convolutional neural network.

European radiology
OBJECTIVE: To present a deep learning-based approach for semi-automatic prostate cancer classification based on multi-parametric magnetic resonance (MR) imaging using a 3D convolutional neural network (CNN).