Tissue engineering and regenerative medicine
32002838
BACKGROUND: Advances in cartilage tissue engineering have demonstrated noteworthy potential for developing cartilage for implantation onto sites impacted by joint degeneration and injury. To supplement resource-intensive in vivo and in vitro studies ...
BACKGROUND: Keratoconus is recognized by asymmetrical thinning and bulging of the cornea, resulting in distortion in the surface of the cornea. Keratoconus also alters the biomechanical properties of the cornea, which can be an indicator of the healt...
The basic requirements for mechanical design and control strategy are adapting to human joint movements and building an interaction model between human and robot. In this paper, a 3-UPS parallel mechanism is adopted to realize that the instantaneous ...
Various methods based on hyperelastic assumptions have been developed to address the mathematical complexities of modeling motion and deformation of continuum manipulators. In this study, we propose a quasistatic approach for 3D modeling and real-tim...
The bodies of earthworms are composed of repeating deformable structural units, called metameres, that generate the peristaltic body motions required for limbless underground burrowing and above-ground crawling. Metameres are actuated by circular and...
This paper presents a human-mimetic manipulator capable of shock absorption by using dislocation at the soft joint. A one degree-of-freedom (DOF) soft robot joint was developed based on the human elbow-joint structure, especially mimicking the humero...
Biomechanics and modeling in mechanobiology
31823106
Real-time simulation of organs increases comfort and safety for patients during the surgery. Proper generalized decomposition (PGD) is an efficient numerical method with coordinate errors below 1 mm and response time below 0.1 s that can be used for ...
We investigate a novel computational approach to computational structural optimization based on deep learning. After employing algorithms to solve the stiffness formulation of structures, we used their improvement to optimize the structural computati...
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
32436783
This study reports the development of an artificial neural network computation model to predict the accumulation of crack density and crack length in cancellous bone under a cyclic load. The model was then applied to conduct a parametric investigatio...
Although three-dimensional (3D) bioprinting technology is rapidly developing, the design strategies for biocompatible 3D-printable bioinks remain a challenge. In this study, we developed a machine learning-based method to design 3D-printable bioink u...