BACKGROUND: Osteoporosis is an asymptomatic disease of high prevalence and incidence, leading to bone fractures burdened by high mortality and disability, mainly when several subsequent fractures occur. A fragility fracture predictive model, Artifici...
Remora suckerfish can attach to a wide diversity of marine hosts, however, their detachment mechanism remains poorly understood. Through analyzing high-speed videos, we found that the detachment of the live remora (Echeneis naucrates) is a rapid beha...
Computer methods in biomechanics and biomedical engineering
Aug 10, 2020
In order to have research on the deformation characteristics and mechanical properties of human red blood cells (RBCs), finite element models of RBC optical tweezers stretching and atomic force microscope (AFM) indentation were established. Non-linea...
International journal of computer assisted radiology and surgery
Jun 8, 2020
PURPOSE: The development of straightforward classification methods is needed to identify unstable aneurysms and rupture risk for clinical use. In this study, we aim to investigate the relative importance of geometrical, hemodynamic and clinical risk ...
Although three-dimensional (3D) bioprinting technology is rapidly developing, the design strategies for biocompatible 3D-printable bioinks remain a challenge. In this study, we developed a machine learning-based method to design 3D-printable bioink u...
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
May 21, 2020
This study reports the development of an artificial neural network computation model to predict the accumulation of crack density and crack length in cancellous bone under a cyclic load. The model was then applied to conduct a parametric investigatio...
We investigate a novel computational approach to computational structural optimization based on deep learning. After employing algorithms to solve the stiffness formulation of structures, we used their improvement to optimize the structural computati...
Biomechanics and modeling in mechanobiology
Dec 10, 2019
Real-time simulation of organs increases comfort and safety for patients during the surgery. Proper generalized decomposition (PGD) is an efficient numerical method with coordinate errors below 1 mm and response time below 0.1 s that can be used for ...
This paper presents a human-mimetic manipulator capable of shock absorption by using dislocation at the soft joint. A one degree-of-freedom (DOF) soft robot joint was developed based on the human elbow-joint structure, especially mimicking the humero...
Tissue engineering and regenerative medicine
Oct 5, 2019
BACKGROUND: Advances in cartilage tissue engineering have demonstrated noteworthy potential for developing cartilage for implantation onto sites impacted by joint degeneration and injury. To supplement resource-intensive in vivo and in vitro studies ...
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