Single-cell transcriptomics technologies have vast potential in advancing our understanding of cellular heterogeneity in complex tissues. While methods to interpret single-cell transcriptomics data are developing rapidly, challenges in most analysis ...
Multi-label proteins can participate in carrier transportation, enzyme catalysis, hormone regulation and other life activities. Meanwhile, they play a key role in the fields of biopharmaceuticals, gene and cell therapy. This article proposes a predic...
MOTIVATION: mRNA location corresponds to the location of protein translation and contributes to precise spatial and temporal management of the protein function. However, current assignment of subcellular localization of eukaryotic mRNA reveals import...
European review for medical and pharmacological sciences
Sep 1, 2021
OBJECTIVE: This paper aims to develop four prediction models for recovered and unrecovered cases using descriptive data of patients and symptoms of CoVID-19 patients. The developed prediction models aim to extract the important variables in predictin...
BACKGROUND: Despite the kidney supply shortage, 18%-20% of deceased donor kidneys are discarded annually in the United States. In 2018, 3569 kidneys were discarded.
Stroke patients vary considerably in terms of outcomes: some patients present 'natural' recovery proportional to their initial impairment (fitters), while others do not (non-fitters). Thus, a key challenge in stroke rehabilitation is to identify indi...
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
Jul 30, 2021
OBJECTIVE: According to the digital image features of corneal opacity, a multi classification model of support vector machine (SVM) was established to explore the objective quantification method of corneal opacity.
Frontiers in bioscience (Landmark edition)
Jul 30, 2021
: The prediction of interacting drug-target pairs plays an essential role in the field of drug repurposing, and drug discovery. Although biotechnology and chemical technology have made extraordinary progress, the process of dose-response experiments ...
Enzyme-catalyzed synthesis reactions are of crucial importance for a wide range of applications. An accurate and rapid selection of optimal synthesis conditions is crucial and challenging for both human knowledge and computer predictions. In this wor...
The accurate quantification of tumor-infiltrating immune cells turns crucial to uncover their role in tumor immune escape, to determine patient prognosis and to predict response to immune checkpoint blockade. Current state-of-the-art methods that qua...
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