AIMC Topic: Synapses
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A multisynaptic spiking neuron for simultaneously encoding spatiotemporal dynamics.
Nature communications
Aug 4, 2025
Spiking neural networks (SNNs) are biologically more plausible and computationally more powerful than artificial neural networks due to their intrinsic temporal dynamics. However, vanilla spiking neurons struggle to simultaneously encode spatiotempor...
Taming the chaos gently: a predictive alignment learning rule in recurrent neural networks.
Nature communications
Jul 23, 2025
Recurrent neural circuits often face inherent complexities in learning and generating their desired outputs, especially when they initially exhibit chaotic spontaneous activity. While the celebrated FORCE learning rule can train chaotic recurrent net...
The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks.
eLife
Jul 4, 2025
Critical network states and neural plasticity enable adaptive behavior in dynamic environments, supporting efficient information processing and experience-dependent learning. Synaptic-weight-based Hebbian plasticity and homeostatic synaptic scaling a...
Microglial pruning of glycinergic synapses disinhibits spinal PKCĪ³ interneurons to drive pain hypersensitivity in mice.
Science translational medicine
Jun 18, 2025
Microglial activation is linked to neuroinflammation in neuropathic pain. Recently, microglia-mediated synaptic pruning has received mounting attention. However, the exact role of spinal microglia in modulating neuropathic pain-associated neural circ...
Concept transfer of synaptic diversity from biological to artificial neural networks.
Nature communications
Jun 2, 2025
Recent developments in artificial neural networks have drawn inspiration from biological neural networks, leveraging the concept of the artificial neuron to model the learning abilities of biological nerve cells. However, while neuroscience has provi...
Neuron-astrocyte associative memory.
Proceedings of the National Academy of Sciences of the United States of America
May 23, 2025
Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might collectivel...
Light-microscopy-based connectomic reconstruction of mammalian brain tissue.
Nature
May 7, 2025
The information-processing capability of the brain's cellular network depends on the physical wiring pattern between neurons and their molecular and functional characteristics. Mapping neurons and resolving their individual synaptic connections can b...
Neuroimaging-derived biological brain age and its associations with glial reactivity and synaptic dysfunction cerebrospinal fluid biomarkers.
Molecular psychiatry
Apr 12, 2025
Magnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other neurodegenerative diseases. However, no previous studies ha...
MXene-enabled organic synaptic fiber for ultralow-power and biochemical-mediated neuromorphic transistor.
Biosensors & bioelectronics
Apr 9, 2025
Fibrous bioelectronic provides an intrinsically accessible platform for artificial nerve and real-time physiological perception. However, advanced fiber-based artificial synapse remains a challenge due to the contradictory conductance demands for bra...
2D Piezo-Ferro-Opto-Electronic Artificial Synapse for Bio-Inspired Multimodal Sensory Integration.
Advanced materials (Deerfield Beach, Fla.)
Apr 7, 2025
Multimodal sensory integration is vital for the evolution of artificial intelligence, yet current approaches often rely on physically connecting distinct sensing units (such as visual and tactile devices) through external circuits, leading to data tr...
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